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Optical coherence photoacoustic microscopy

  • US 10,107,613 B2
  • Filed: 08/30/2016
  • Issued: 10/23/2018
  • Est. Priority Date: 06/15/2011
  • Status: Active Grant
First Claim
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1. A method of optical coherence photoacoustic multi-modal microscopic imaging of a target, the method comprising:

  • generating, substantially simultaneously using a light source, A-scans for optical coherence tomography and photoacoustic microscopy of the target;

    forming, using a processor, B-scan images for optical coherence tomography and photoacoustic microscopy of the target co-registered in a lateral direction and both formed from photons generated from the A-scans; and

    generating, using the processor, a fused image of the target from B-scan image data for optical coherence tomography and photoacoustic microscopy, wherein the photoacoustic microscopy B-scan image data is scaled and interpolated to be co-registered with the B-scan image for optical coherence tomography in a depth direction and to fuse with the optical coherence tomography B-scan data to form a combined optical coherence tomography and photoacoustic microscopy image.

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