Measuring apparatus

• US 10,109,376 B2
• Filed: 04/18/2017
• Issued: 10/23/2018
• Est. Priority Date: 12/21/2016
• Status: Active Grant

• Current Assignee: Milestone S.R.L. (Embracer Group AB)
• Original Assignee: Milestone S.R.L. (Embracer Group AB)
• Inventors: Visinoni, Francesco, Minuti, Matteo, Martinelli, Michele
• Primary Examiner(s): Brown, Claude J
• Application Number:
  US15/489,999
• Publication Number:
  US 20180173851A1
• Time in Patent Office: 553 Days
• Field of Search: 235385
• CPC Class Codes: G01B 11/00 Measuring arrangements characterised by the use of optical techniques
• CPC Class Codes: G01N 1/31 Apparatus therefor
• CPC Class Codes: G01N 1/312 for samples mounted on planar substrates
• CPC Class Codes: G01N 2001/315 Basket-type carriers for tissues
• CPC Class Codes: G01N 2035/00138 Slides
• CPC Class Codes: G01N 2035/00742 Type of codes
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 2035/00821 nature of coded information
• CPC Class Codes: G01N 33/4833 of solid biological material, e.g. tissue samples, cell cultures tissue in vivo A61B5/00; cell suspensions G01N33/48735
• CPC Class Codes: G01N 33/5005 involving human or animal cells immunoassay G01N33/56966; immunoassays of protozoa G01N33/56905; protozoa in screening assays C12Q1/025
• CPC Class Codes: G01N 33/56966 Animal cells
• CPC Class Codes: G01N 35/00732 Identification of carriers, materials or components in automatic analysers
• CPC Class Codes: G06K 7/10722 Photodetector array or CCD scanning
• CPC Class Codes: G06K 7/10861 sensing of data fields affixed to objects or articles, e.g. coded labels postal sorting B07C3/14, conveying articles B65G47/48
• CPC Class Codes: G06Q 10/087 Inventory or stock management, e.g. order filling, procurement or balancing against orders
• CPC Class Codes: G16H 40/20 for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms

Abstract

Measuring apparatus (1) for tracking human and/or animal tissues comprising: a working area (2) for receiving a tissue; a detecting unit (5) configured to detect a unique tissue code provided with the tissue placed on the working area (2); a measuring unit (9) configured to automatically measure quantitative properties of the tissue placed on the working area (2); and a processing and storing unit (22) configured to automatically link the quantitative properties with the tissue code and to automatically store the so linked quantitative properties and tissue code such that the quantitative properties can be retrieved based on the tissue code.

Claims

1. Measuring apparatus (1) for tracking human and/or animal tissues comprising:

a) a working area (2) for receiving a tissue;

b) a detecting means (5) configured to detect a unique tissue code provided with the tissue placed on the working area (2);

c) a measuring means (9) configured to automatically measure quantitative properties, which include three-dimensional properties, of the tissue placed on the working area (2); and

d) a processing and storing unit (22) configured to automatically link the quantitative properties with the tissue code and to automatically store the so linked quantitative properties and tissue code such that the quantitative properties can be retrieved based on the tissue code.

2. Measuring apparatus (1) according to claim 1, wherein the processing and storing unit (22) is further configured to restore the relation between the tissue code and the tissue based on the quantitative properties being linked with the tissue code.

3. Measuring apparatus (1) according to claim 1, wherein the measuring means (9) is an optical measuring means.

4. Measuring apparatus (1) according to claim 1, wherein the measuring means (9) comprises a moving means (10) configured to move the measuring means (9) with respect to the tissue to obtain the quantitative properties of the tissue.

5. Measuring apparatus (1) according to claim 1, wherein the quantitative properties include number of tissues or the combination thereof.

6. Measuring apparatus (1) according to claim 5, wherein the quantitative properties include length, width, thickness, area, and/or volume, shape, holes, bulkiness, eccentricity, center, centroid, circularity, rectangularity, roundness, symmetry, compactness, convexity, distance variance, distance standard deviation, distance covariance, distance mean, Euler characteristic, equivalent ellipse, maximum inscribed circle, minimum circumscribed circle, maximum inscribed sphere, minimum circumscribed sphere, sides number, faces number, contour length, orientation, or geometric moments or a combination thereof.

7. Measuring apparatus (1) according to claim 1, wherein the processing and storing unit (22) comprises a data carrier configured to store the linked quantitative properties and tissue code.

8. Measuring apparatus (1) according to claim 7, wherein the data carrier is remotely provided as a server.

9. Measuring apparatus (1) according to claim 1, wherein the detecting means (5) is an optical reader configured to take a picture of the tissue received by the working area (2).

10. Measuring apparatus (1) according to claim 1, wherein the tissue code is a one- or two-dimensional barcode or wherein the tissue code is provided by means of near field technology.

11. Measuring apparatus (1) according claim 1, wherein the tissue code is indirectly connected to the tissue.

12. Measuring apparatus (1) according to claim 11, wherein the tissue code is indirectly connected to the tissue by way of a tissue carrier (4) for carrying the tissue.

13. Measuring system (S) for tracking human and/or animal tissues comprising:

A. a rack (R) designed to receive at least one human and/or animal tissue for tissue processing;

B. a further detecting means (100) configured to detect a unique rack code provided with the rack (R); and

C. a measuring apparatus (1) according to claim 1, wherein the processing and storing unit (22) is further configured to

automatically link the rack code with the tissue code, and

to automatically store the so linked codes, such that the tissue code(s) and thus the respectively linked quantitative properties can be retrieved based on, the rack code.

14. Measuring system (S) according to claim 13 further comprising a user and/or machine interface (200, 300 ) configured to output the quantitative properties and/or the codes.

15. Measuring system (S) according to claim 13, wherein the processing and storing unit (22) is further configured to automatically store the so linked codes, such that the process parameters of tissue processing can be retrieved based on the tissue code(s) and/or the rack code.

16. Measuring apparatus (1) according to claim 1 further comprising a user and/or machine interface (200, 300) configured to output the quantitative properties and/or the codes.

17. Measuring apparatus (1) according to claim 1, wherein the measuring means (9) is configured to measure two- and three-dimensional properties of the tissue.

18. Method for tracking human and/or animal tissues comprising the steps of:

1) placing a tissue on a working area (2);

2) detecting a unique tissue code provided with the tissue by means of a detecting means (5);

3) automatically measuring of quantitative properties of the tissue by means of a measuring means (9), wherein the quantitative properties include three-dimensional properties;

4) automatically linking the quantitative properties with the tissue code by means of a processing and storing unit (22), and

5) automatically storing the so linked quantitative properties and tissue code by means of the processing and storing unit (22) such that the quantitative properties can be retrieved based on the tissue code and optionally such that the relation between the tissue code and the tissue is restored based on the quantitative properties being linked with the tissue code, and optionally retrieving the quantitative properties based on the tissue code.

19. Method according to claim 18 further comprising the steps of:

0) detecting a unique rack code of a rack (R) by means of a further detecting means (100),

6) placing the tissue on the rack (R),

7) automatically linking the tissue code with the rack code by means of the processing and storing unit (22), and

8) automatically storing the so linked codes by way of the processing and storing unit (22) such that the tissue code(s) and thus the respectively linked quantitative properties can be retrieved based on the rack code.

20. Method according to claim 19 further comprising the step of processing the tissues on the rack (R).

21. Method according to claim 20, wherein processing the tissues comprises the steps of

Fixation,

Dehydration,

Clearing, and

Impregnation and/or infiltration.

22. Method according to claim 19, wherein steps 1 to 8 are repeated for a plurality of tissues such that the tissue codes can be retrieved based on the rack code.

23. Method according to claim 20, wherein the method further comprises the steps of automatically linking process parameters of the tissue processing with the rack code and also with the tissue code(s), and of storing the so linked process parameters and code(s) such that the process parameters can be retrieved based on the code(s).