Hybrid orientation paravalvular sealing stent

• US 10,117,743 B2
• Filed: 06/27/2014
• Issued: 11/06/2018
• Est. Priority Date: 07/01/2013
• Status: Active Grant

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Inventors: Kumar, Saravana B., Khouengboua, Sounthara
• Primary Examiner(s): Sharma, Yashita
• Assistant Examiner(s): Preston, Rebecca
• Application Number:
  US14/901,287
• Publication Number:
  US 20160158004A1
• Time in Patent Office: 1,593 Days
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2210/0057 stretchable
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/001 for adjusting a diameter
• CPC Class Codes: A61F 2250/0018 differing in elasticity, stiffness or compressibility
• CPC Class Codes: A61F 2250/0029 differing in bending or flexure capacity
• CPC Class Codes: A61F 2250/0036 differing in thickness
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0096 Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers

Abstract

A prosthetic heart valve (300) for replacing a native heart valve includes a collapsible and expandable stent (306) extending in a length direction between a proximal end (302) and a distal end (304), the stent (306) including a plurality of struts (320) defining a plurality of cells (330), the plurality of cells (330) forming an aortic section (310), an annulus section (314) and a subannular section (316) of the stent (306). A valve assembly is disposed within the annulus section (314) of the stent (306), the valve assembly including a plurality of leaflets. In an expanded condition of the stent, each of the plurality of cells of the subannular section (316) has a width greater than its length, and each of the plurality of cells of the annulus section (314) has a length greater than its width.

Claims

1. A prosthetic heart valve for replacing a native valve, comprising:

a collapsible and expandable stent extending in a length direction between a proximal end and a distal end, the stent including a plurality of struts defining a plurality of cells, the plurality of cells forming an aortic section, an annulus section and a subannular section of the stent, each of the cells having a length in the length direction and a width in a circumferential direction of the stent, the annulus section having a first diameter in an expanded condition of the stent, the aortic section having a second diameter in the expanded condition of the stent larger than the first diameter, each of the plurality of cells in the aortic section being larger than each of the plurality of cells in the annulus section; and

a valve assembly directly coupled to the annulus section of the stent, the valve assembly including a plurality of leaflets;

wherein, in the expanded condition of the stent, each of the plurality of cells of the subannular section has a width greater than its length, and each of the plurality of cells of the annulus section has a length greater than its width,

wherein the struts of the subannular section have an average thickness less than an average thickness of the struts of the annulus section.

2. The prosthetic heart valve of claim 1, wherein the plurality of cells include a plurality of mitre-shaped transition cells disposed between the annulus section and the subannular section.

3. The prosthetic heart valve of claim 1, wherein the plurality of cells of the subannular section in the expanded condition are generally oval-shaped with upper and lower peaks.

4. The prosthetic heart valve of claim 1, wherein the average thickness of the struts of the subannular section between about ⅓

to about ½

of the average thickness of struts of the annulus section.

5. The prosthetic heart valve of claim 1, wherein the subannular section is configured and arranged to be disposed below leaflets of the native valve when the prosthetic valve replaces the native valve.

6. A prosthetic heart valve for replacing a native valve, comprising:

a collapsible and expandable stent having a proximal end, a distal end, and a plurality of struts defining a plurality of cells, the plurality of cells forming an aortic section, an annulus section and a subannular section of the stent, the annulus section having a first diameter in an expanded condition of the stent, the aortic section having a second diameter in the expanded condition of the stent larger than the first diameter, each of the plurality of cells in the aortic section being larger than each of the plurality of cells in the annulus section; and

a valve assembly disposed within the annulus section of the stent, the valve assembly including a plurality of leaflets,

wherein the struts of the annulus section have a first average thickness and the struts of the subannular section have a second average thickness different from the first average thickness,

wherein the second average thickness is between about ⅓

to about 1/2 of the first average thickness.

7. A prosthetic heart valve for replacing a native valve, comprising:

a collapsible and expandable stent extending in a length direction between a proximal end and a distal end, the stent including a plurality of struts defining a plurality of cells, the plurality of cells forming an aortic section, an annulus section and a subannular section of the stent; and

a valve assembly disposed within the annulus section of the stent, the valve assembly including a plurality of leaflets,

wherein the subannular section in an expanded condition of the stent has a larger diameter than the annulus section in the expanded condition of the stent,

wherein each of the plurality of cells has a length in the length direction and a width in a circumferential direction of the stent, and for each of the plurality of cells of the subannular section the length is between about 5 mm and about 12 mm and the width is between about 9 mm and about 16 mm in the expanded condition.

8. The prosthetic heart valve of claim 7, wherein the subannular section in the expanded condition of the stent has a diameter between about 2 mm and about 6 mm larger than a diameter of the annulus section in the expanded condition of the stent.

9. The prosthetic heart valve of claim 7, wherein for each of the plurality of cells of the subannular section the length is less than the width in the expanded condition.