Cannabinoid composition for treating pain

• US 10,117,891 B2
• Filed: 09/16/2015
• Issued: 11/06/2018
• Est. Priority Date: 09/16/2014
• Status: Active Grant

• Current Assignee: India Globalization Capital, Inc.
• Original Assignee: India Globalization Capital, Inc.
• Inventors: Mukunda, Ramachandra, Krishna, Ranga Chelva
• Primary Examiner(s): Lau, Jonathan S
• Application Number:
  US15/104,554
• Publication Number:
  US 20170027978A1
• Time in Patent Office: 1,147 Days
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/05 Phenols cannabinoids A61K31/658
• CPC Class Codes: A61K 31/352 condensed with carbocyclic rings, e.g. methantheline cannabinoids A61K31/658
• CPC Class Codes: A61K 31/714 Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 47/44 Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61P 19/02 for joint disorders, e.g. arthritis, arthrosis
• CPC Class Codes: A61P 25/00 Drugs for disorders of the nervous system
• CPC Class Codes: A61P 25/02 for peripheral neuropathies

Abstract

A combination of THC, CBD and Cobalamin (in a ratio of about 63%, 27% and 10%, respectively) is used with a topical carrier such as Shea butter cream to relieve pain. The THC and CBD mixture is extracted from a Cannabis Indica dominant strain using high pressure and carbon dioxide (CO₂) as a solvent and comprises: Tetrahydrocannabinol “THC” (9-Tetrahydrocannabinol (delta-9 THC), 8-Tetrahydrocannabinol (Delta-8 THC) and 9-THC Acid), Cannabidiol “CBD”, Cannabinol “CBN”, Cannabichromene (“CBC”), Cannabigerol (“CBG”), terpenoids and flavonoids. The Shea butter is an extract from the Shea nut from the Shea tree (Vitellaria paradoxa).

Claims

1. A topical composition for treating pain consisting essentially of:

(i) tetrahydrocannabinol (THC) in an amount from about 50% to about 70% by weight;

(ii) cannabidiol (CBD) in an amount from about 20% to about 40% by weight;

(iii) cobalamin in an amount from about 5% to about 20% by weight and (iv) a carrier wherein the percentage amounts of THC, CBD and cobalamin is based on the total weight of THC, CBD and cobalamin in the composition.

2. Composition of claim 1 wherein THC is used in an amount greater than CBD and cobalamin is used in an amount less that either of THC or CBD.

3. Composition of claim 2 wherein THC is used in an amount greater the 50% by weight, CBD in an amount up to about 30% by weight and cobalamin in an amount up to about 20% by weight.

4. Composition of claim 3 wherein THC is used in an amount of about 63% by weight, CBD in an amount of about 27% and cobalamin in an amount of about −

11%.

5. Composition of claim 1 wherein THC and CBD are extracted from Cannabis Sativa.

6. Composition of claim 1 wherein THC and CBD are synthetic.

7. Composition of claim 1 wherein CBD is organic CBD also containing cannabinol (CBN), cannabichromene (CBC), cannabigerol (CBG), terpenoids and flavonoids.