Neuromodulation using modulated pulse train

• US 10,118,040 B2
• Filed: 02/07/2017
• Issued: 11/06/2018
• Est. Priority Date: 03/08/2013
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Zhu, Changfang
• Primary Examiner(s): Manuel, George
• Application Number:
  US15/426,776
• Publication Number:
  US 20170143964A1
• Time in Patent Office: 637 Days
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36178 Burst or pulse train parameters
• CPC Class Codes: A61N 1/36189 using modulation techniques
• CPC Class Codes: A61N 1/36192 Amplitude modulation
• CPC Class Codes: A61N 1/36196 Frequency modulation
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: H05K 999/99 dummy group

Abstract

A neuromodulation system comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes, a user interface configured for receiving input from a user that selects one of a plurality of different shapes of a modulating signal and/or selects one of a plurality of different electrical pulse parameters of an electrical pulse train, neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals, and pulse train modulation circuitry configured for modulating the electrical pulse train in accordance with the selected shape of the modulating signal and/or selected electrical pulse parameter of the electrical pulse train.

Claims

1. A device configured for communicating with a neuromodulator that includes neuromodulation output circuitry configured to output an electrical pulse train having electrical pulse parameters, and pulse train modulation circuitry configured to modulate one or more electrical pulse parameters of the electrical pulse train with a modulation signal, the device comprising:

a user interface configured to enable a user to select a modulation adjustment mode selected from more than one modulation adjustment mode, wherein the more than one modulation adjustment mode includes a pulse train modulation mode configured to enable a user to select;

the one or more of the electrical pulse parameters of the electrical pulse train to be modulated with the modulation signal;

a shape of the modulation signal used to modulate the one or more of the electrical pulse parameters of the electrical pulse train;

or

both the one or more of the electrical pulse parameters to be modulated with the modulation signal and the shape of the modulation signal used to modulate the one or more of the electrical pulse parameters of the electrical pulse train.

2. The device of claim 1 wherein the user interface is configured to present selectable shapes of the modulation signal, and to enable a user to select one of the selectable shapes of the modulation signal.

3. The device of claim 2 wherein the selectable shapes include at least one of a sinusoidal wave, a triangular wave, or a ramped wave.

4. The device of claim 3 wherein the user interface is configured to provide at least one check box to enable the user to select one of the selectable shapes of the modulation signal.

5. The device of claim 1 wherein the one or more of the electrical pulse parameters to be modulated include at least one of an upper limit of a modulation shape, a lower limit of a modulation shape, or a period of a modulation signal.

6. The device of claim 1 wherein the user interface is configured to present selectable modulation parameters to enable a user to select one or more electrical pulse parameters to be modulated.

7. The device of claim 6 wherein the selectable modulation parameters enable a user to select one or more of a pulse amplitude to be modulated, a pulse rate to be modulated, or a pulse duration to be modulated.

8. A device configured for communicating with a neuromodulator that includes neuromodulation output circuitry configured to output an electrical pulse train, and pulse train modulation circuitry configured to modulate one or more electrical pulse parameters of the electrical pulse train with a modulation signal, the device comprising:

a user interface configured to receive at least one of a shape selection from the user or a selection from the user of the one or more electrical pulse parameters of the electrical pulse train to be modulated with the modulation signal, wherein the shape selection is a selected one of a group of preprogrammed shapes for use as a shape of the modulation signal used to modulate the electrical pulse train; and

communication circuitry configured to communicate a signal indicative of the at least one of;

the shape selection to the neuromodulator for use as the shape of the modulation signal used to modulate the one or more electrical pulse parameters of the electrical pulse train, or

the selection from the user of the one or more of the electrical pulse parameters of the electrical pulse train to be modulated.

9. The device of claim 8 wherein the user interface is configured to present selectable shapes of the modulation signal, and to enable a user to select one of the selectable shapes of the modulation signal.

10. The device of claim 9 wherein the selectable shapes include at least one of a sinusoidal wave, a triangular wave, or a ramped wave.

11. The device of claim 10 wherein the user interface is configured to provide at least one check box to enable the user to select one of the selectable shapes of the modulation signal.

12. The device of claim 8 wherein one or more electrical pulse parameters of the electrical pulse train to be modulated include at least one of an upper limit of a modulation shape, a lower limit of a modulation shape, or a period of a modulation signal.

13. The device of claim 8 wherein the user interface is configured to present selectable modulation parameters to enable a user to select one or more electrical pulse parameters of the electrical pulse train to be modulated.

14. The device of claim 13 wherein the selectable modulation parameters enable a user to select one or more of a pulse amplitude to be modulated, a pulse rate to be modulated, or a pulse duration to be modulated.

15. A non-transient machine readable medium containing instructions, which when executed by the machine, cause the machine to communicate with a neuromodulator that includes neuromodulation output circuitry configured to output an electrical pulse train having electrical pulse parameters, and pulse train modulation circuitry configured to modulate one or more of the electrical pulse parameters of the electrical pulse train with a modulation signal, wherein the instructions, which when executed by the machine, cause the machine to:

receive via a user interface at least one of a shape selection from the user or a selection of the one or more of the electrical pulse parameters of the electrical pulse train to be modulated, wherein the shape selection is a selected one of a group of preprogrammed shapes for use as a shape of the modulation signal used to modulate the one or more of the electrical pulse parameters of the electrical pulse train; and

communication circuitry configured to communicate a signal indicative of the at least one of;

the shape selection to the neuromodulator for use as the shape of the modulation signal used to modulate the one or more electrical pulse parameters of the electrical pulse train, or

the selection from the user of the one or more of the electrical pulse parameters of the electrical pulse train to be modulated.

16. The non-transient machine readable medium of claim 15 wherein the instructions, which when executed by the machine, cause the machine to present selectable shapes of the modulation signal on the user interface, and to enable a user to select one of the selectable shapes of the modulation signal.

17. The non-transient machine readable medium of claim 16 wherein the selectable shapes of the modulation signal includes a sinusoidal wave, a triangular wave, or a ramped wave.

18. The non-transient machine readable medium of claim 17 wherein the instructions, which when executed by the machine, cause the machine to provide at least one check box on the user interface to enable the user to select one of the selectable shapes of the modulation signal.

19. The non-transient machine readable medium of claim 15 wherein the one or more of the electrical pulse parameters to be modulated include at least one of an upper limit of a modulation shape, a lower limit of a modulation shape, or a period of a modulation signal.

20. The non-transient machine readable medium of claim 15 wherein the instructions, which when executed by the machine, cause the machine to present selectable modulation parameters on the user interface to enable a user to select one or more electrical pulse parameters to be modulated.