Neurostimulation lead with conductive elements and methods for making the same

• US 10,124,161 B2
• Filed: 03/31/2017
• Issued: 11/13/2018
• Est. Priority Date: 03/31/2016
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Barker, John M.
• Primary Examiner(s): Mahmood, Nadia A
• Application Number:
  US15/476,328
• Publication Number:
  US 20170281929A1
• Time in Patent Office: 592 Days
• Field of Search: 607116
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer
• CPC Class Codes: C07K 16/32 against translation products of oncogenes
• CPC Class Codes: C07K 16/40 against enzymes
• CPC Class Codes: C07K 2317/24 containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
• CPC Class Codes: C07K 2319/30 Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
• CPC Class Codes: C07K 2319/50 containing protease site
• CPC Class Codes: C12N 9/50 Proteinases , e.g. Endopeptidases (3.4.21-3.4.25)

Abstract

A lead includes a ribbon cable comprising a distal end portion and a proximal end portion. The ribbon cable has a plurality of conductors disposed within an insulating body and a plurality of electrode apertures selectively disposed along the distal end portion of the insulating body. The ribbon cable further includes a plurality of conductive electrodes, wherein each of the plurality of conductive electrodes is disposed over at least one of the plurality of electrode apertures and in electrical communication with at least one of the plurality of conductors. The lead may optionally include a flexible, flat lead body. A method of making a lead includes the steps of (1) obtaining a ribbon cable comprising a plurality of conductors; (2) selectively removing regions of the insulating body to create a plurality of apertures; and (3) placing a plurality of conductive elements over the plurality of apertures, respectively.

Claims

1. A lead comprising:

a ribbon cable comprising a distal end portion and a proximal end portion, the ribbon cable comprising an insulating body and a plurality of conductors disposed within the insulating body and extending longitudinally from the distal end portion of the ribbon cable to the proximal end portion of the ribbon cable, the ribbon cable further comprising a plurality of electrode apertures selectively disposed along the distal end portion of the ribbon cable, wherein each of the conductors is a wire or multi-filar cable; and

a plurality of conductive electrodes, wherein each of the plurality of conductive electrodes is disposed over at least one of the plurality of electrode apertures and in electrical communication with at least one of the plurality of conductors.

2. The lead of claim 1, further comprising a plurality of conductive terminals selectively disposed along the proximal end portion of the ribbon cable, wherein each of the plurality of conductive terminals is in electrical communication with at least one of the plurality of conductors.

3. The lead of claim 1, wherein the ribbon cable further comprises a plurality of terminal apertures selectively disposed along the proximal end portion of the ribbon cable.

4. The lead of claim 3, further comprising a plurality of conductive terminals, wherein each of the plurality of conductive terminals is disposed over at least one of the plurality of terminal apertures and in electrical communication with at least one of the plurality of conductors.

5. The lead of claim 1, wherein the plurality of electrode apertures are staggered with respect to each other in a longitudinal direction along the insulating body.

6. The lead of claim 1, wherein at least one of the plurality of conductive electrodes is a conductive polymer electrode.

7. The lead of claim 6, wherein the conductive polymer electrode is made of a conductive epoxy.

8. The lead of claim 6, wherein the conductive polymer electrode is made of a polymeric material mixed with a conductive material.

9. The lead of claim 1, wherein at least one of the plurality of conductive electrodes extends at least from one edge of the ribbon cable to an opposite edge of the ribbon cable.

10. The lead of claim 1, wherein the distal end portion of the ribbon cable is shaped in a generally planar configuration.

11. The lead of claim 2, wherein the proximal end portion of the ribbon cable is shaped in a cylindrical configuration.

12. The lead of claim 1, wherein at least one of the plurality of conductive electrodes extends completely around the insulating body.

13. An electrical stimulation system comprising:

the lead of claim 1; and

a control module comprising a housing and an electronic subassembly disposed in the housing.

14. The electrical stimulation system of claim 13, wherein at least one of the plurality of conductive electrodes is a conductive polymer electrode.

15. A lead comprising:

a flexible, flat lead body comprising a distal end portion and a proximal end portion, the lead body comprising a plurality of conductors disposed within an insulation covering with the conductors lying parallel to each other along the distal end portion, the lead body further comprising a plurality of electrode apertures selectively disposed along the distal end portion of the lead body; and

a plurality of conductive electrodes, wherein each of the plurality of conductive electrodes is disposed over at least one of the plurality of electrode apertures and in electrical communication with at least one of the plurality of conductors.

16. The lead of claim 15, further comprising a plurality of conductive terminals selectively disposed along the proximal end portion of the lead body, wherein each of the plurality of conductive terminals is in electrical communication with at least one of the plurality of conductors.

17. The lead of claim 16, further comprising the lead body comprising a plurality of terminal apertures selectively disposed along the proximal end portion of the insulation covering.

18. The lead of claim 17, further comprising a plurality of conductive terminals, wherein each of the plurality of conductive terminals is disposed over at least one of the plurality of terminal apertures and in electrical communication with at least one of the plurality of conductors.

19. A method of making a lead, the method comprising:

obtaining a ribbon cable comprising a plurality of conductors disposed within an insulating body;

selectively removing regions of the insulating body to create a plurality of apertures that expose the plurality of conductors; and

placing a plurality of conductive elements over the plurality of apertures, wherein each conductive element is in electrical communication with each conductor in the ribbon cable, respectively.

20. The method of claim 19, wherein placing the plurality of conductive elements over the plurality of apertures include applying a conductive polymeric material over the plurality of apertures.