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Systems and methods for biological analysis and computation

  • US 10,125,393 B2
  • Filed: 12/10/2014
  • Issued: 11/13/2018
  • Est. Priority Date: 12/11/2013
  • Status: Active Grant
First Claim
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1. A microfluidic device, comprising:

  • (a) a chamber comprising (i) a first surface having a width (W) and a length (L), (ii) a second surface parallel to the first surface, and (iii) a space between the first surface and the second surface having a height (H), wherein the space between the first surface and second surface is configured to direct fluid flow and H is less than about 3 millimeters (mm); and

    (b) an input funnel having (i) a wide end spanning the width of the first surface and in fluid communication with the space between the first surface and the second surface, and (ii) a narrow end medial to the wide end and in fluid communication with the wide end, wherein the wide end has a first thickness (t0) at its mid-point, a second thickness (t1) at its edges, and a height (h) between the wide end to the narrow end,wherein (t0) is less than (t1).

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