Medical device for analyte monitoring and drug delivery
First Claim
1. An ingestible medical device, comprising:
- a microchip enclosed in the ingestible medical device, the microchip comprising an interface device that is configured to wirelessly transmit a signal that is generated upon interaction of the device with gastric fluid to an external device located outside the subject, and is configured to transmit a physiological condition of the subject anda biocompatible coating covering at least a portion of the device, wherein a portion of the coating is characterized by interconnected pores of sufficient size to allow for flow of bodily fluids into the ingestible medical device and another portion of the coating covering a larger portion of device that is not porous,wherein in response to being ingested by a subject, the device is configured to interact with a gastric fluid, andwherein the device is configured to measure the physiological condition of the subject.
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Accused Products
Abstract
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid; and an interface device.
93 Citations
14 Claims
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1. An ingestible medical device, comprising:
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a microchip enclosed in the ingestible medical device, the microchip comprising an interface device that is configured to wirelessly transmit a signal that is generated upon interaction of the device with gastric fluid to an external device located outside the subject, and is configured to transmit a physiological condition of the subject and a biocompatible coating covering at least a portion of the device, wherein a portion of the coating is characterized by interconnected pores of sufficient size to allow for flow of bodily fluids into the ingestible medical device and another portion of the coating covering a larger portion of device that is not porous, wherein in response to being ingested by a subject, the device is configured to interact with a gastric fluid, and wherein the device is configured to measure the physiological condition of the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification