Monoazo dyes with cyclic amine as fluorescence quencers
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Abstract
The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.
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- 1. A compound having the formula:
- 3. A compound having the formula:
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5. A compound having the formula:
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6. A compound having the formula:
Specification