Microneedle arrays for biosensing and drug delivery
First Claim
1. An analyte-selective sensor device, comprising:
- a substrate that includes at least one microneedle with a hollowed interior, wherein the at least one microneedle comprises an interior wall with an opening to the hollowed interior;
an electrode comprising a probe, wherein the probe is disposed inside the hollowed interior and spaced away from the interior wall, wherein the electrode is functionalized by a coating comprising an enzyme-functionalized coating or an ion-selective coating over at least the probe to interact with an analyte to produce an electrical signal; and
a wire electrically coupled to the probe operable to transfer the electrical signal.
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Accused Products
Abstract
Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.
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Citations
8 Claims
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1. An analyte-selective sensor device, comprising:
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a substrate that includes at least one microneedle with a hollowed interior, wherein the at least one microneedle comprises an interior wall with an opening to the hollowed interior; an electrode comprising a probe, wherein the probe is disposed inside the hollowed interior and spaced away from the interior wall, wherein the electrode is functionalized by a coating comprising an enzyme-functionalized coating or an ion-selective coating over at least the probe to interact with an analyte to produce an electrical signal; and a wire electrically coupled to the probe operable to transfer the electrical signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification