Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
DCFirst Claim
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1. A method of treating acne vulgaris, comprising administering a surfactant free foam composition dispensed from a container, wherein the container comprises:
- i) a carrier comprising;
a) about 60% to about 95% by weight of the carrier of a hydrophobic solvent, wherein the hydrophobic solvent is an oil;
b) about 0.1% to about 20% by weight of the carrier of at least one fatty alcohol,wherein the fatty alcohol has a carbon chain length of 14 to 22 carbons;
c) about 0.1% to about 20% by weight of the carrier of at least one fatty acid, at least one wax, at least one shea butter, or mixtures of two or more thereof, wherein the fatty acid has a carbon chain length of 12 to 28 carbons, and the wax is selected from the group consisting of a beeswax, a hydrogenated castor oil, a paraffin wax, a wax that is solid at room temperature, and a mixture of any two or more thereof; and
d) a minocycline antibiotic; and
ii) a liquefied or compressed gas propellant;
wherein the composition comprises 15% or less of petrolatum by weight of the carrier;
wherein the composition is essentially waterless;
wherein the composition is free of polymeric agent;
and wherein, upon dispensing, the composition forms a foam.
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Abstract
A substantially surface active agent free composition which includes a hydrophobic solvent, and/or a petrolatum, a paraffin wax and/or a fatty alcohol, a fatty acid and/or a wax and/or shea butter, with and without a propellant. A substantially surface active agent free composition, further comprising, a tetracycline antibiotic, or a vitamin D derivative, or one or more other active agents. A method of treatment using a substantially surface active agent free composition.
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Citations
21 Claims
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1. A method of treating acne vulgaris, comprising administering a surfactant free foam composition dispensed from a container, wherein the container comprises:
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i) a carrier comprising; a) about 60% to about 95% by weight of the carrier of a hydrophobic solvent, wherein the hydrophobic solvent is an oil; b) about 0.1% to about 20% by weight of the carrier of at least one fatty alcohol, wherein the fatty alcohol has a carbon chain length of 14 to 22 carbons; c) about 0.1% to about 20% by weight of the carrier of at least one fatty acid, at least one wax, at least one shea butter, or mixtures of two or more thereof, wherein the fatty acid has a carbon chain length of 12 to 28 carbons, and the wax is selected from the group consisting of a beeswax, a hydrogenated castor oil, a paraffin wax, a wax that is solid at room temperature, and a mixture of any two or more thereof; and d) a minocycline antibiotic; and ii) a liquefied or compressed gas propellant; wherein the composition comprises 15% or less of petrolatum by weight of the carrier; wherein the composition is essentially waterless; wherein the composition is free of polymeric agent; and wherein, upon dispensing, the composition forms a foam. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification