Flow based pressure isolation and fluid delivery system including flow based pressure isolation and flow initiating mechanism

• US 10,137,294 B2
• Filed: 12/20/2016
• Issued: 11/27/2018
• Est. Priority Date: 10/18/2001
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Spohn, Michael A., Haury, John A.
• Primary Examiner(s): MCCALISTER, WILLIAM M
• Application Number:
  US15/385,153
• Publication Number:
  US 20170100577A1
• Time in Patent Office: 707 Days
• Field of Search: 13751625, 13751627, 137519, 137485, 137877, 1375195, 600485, 600486, 600487, 600488, 604140
• CPC Class Codes: A61B 5/02141 Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits A61B5/02233, A61B5/0235 take precedence
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61M 2005/1403 Flushing or purging
• CPC Class Codes: A61M 2039/229 Stopcocks
• CPC Class Codes: A61M 2039/2433 Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
• CPC Class Codes: A61M 2039/2453 not being fixed to the valve body
• CPC Class Codes: A61M 2039/2473 Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
• CPC Class Codes: A61M 2039/248 Ball-valve
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3362 with minimised length of fluid lines; Taking into account the elastic expansion of fluid lines to increase accuracy
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/16881 : Regulating valves on-off valves, e.g. clamps A61M39/28
• CPC Class Codes: A61M 5/172 : electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/365 : Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626
• CPC Class Codes: Y10T 137/0352 : Controlled by pressure
• CPC Class Codes: Y10T 137/7758 : Pilot or servo controlled
• CPC Class Codes: Y10T 137/7871 : Weight biased
• CPC Class Codes: Y10T 137/7915 : Guide stem
• CPC Class Codes: Y10T 137/85978 : With pump
• CPC Class Codes: Y10T 137/87829 : Biased valve

Abstract

A method for protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism is disclosed. The method includes associating the pressure transducer with an isolation port of the pressure isolation mechanism, placing a pressurizing device for delivering fluid under pressure in fluid connection with an inlet port of the pressure isolation mechanism, and actuating the pressurizing device to cause fluid flow in the inlet port such that a free floating, fluid flow responsive valve member positioned in an internal cavity of the pressure isolation mechanism engages a seal seat therein to attain a closed position, preventing fluid flow between the inlet port and the isolation port and thus prevent overpressure in the isolation port. Hemodynamic pressure signals read with the pressure transducer may be transmitted at least in part through a body of the valve member, or a portion thereof, when in the closed position.

Claims

1. A method of protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism comprising an inlet port, an isolation port, and an internal cavity wherein a free floating, fluid flow responsive valve member is disposed and adapted to engage a seal seat in the internal cavity, and a flow initiating mechanism is associated with the isolation port, the method comprising:

associating the pressure transducer with the isolation port;

placing a pressurizing device for delivering fluid under pressure in fluid connection with the inlet port;

actuating the pressurizing device to cause fluid flow in the inlet port such that the free floating, fluid flow responsive valve member engages the seal seat to attain a closed position, to prevent fluid flow between the inlet port and the isolation port, and to prevent overpressure in the isolation port; and

reading hemodynamic pressure signals with the pressure transducer transmitted at least in part through a body of the valve member or a portion thereof in the closed position,

wherein upon actuation of the pressurizing device, the flow initiating mechanism initiates flow around the valve member such that the valve member operates to the closed position upon fluid flow initiation.

2. The method of claim 1, further comprising deactuating the pressurizing device and allowing the valve member to attain an open position disengaged from the seal seat permitting fluid communication between the inlet port and the isolation port.

3. The method of claim 2, further comprising reading hemodynamic pressure signals with the pressure transducer transmitted via the fluid communication between the inlet port and the isolation port in the open position of the valve member.

4. The method of claim 1, wherein the body of the valve member or a portion thereof comprises a compliant material.

5. The method of claim 4, wherein the compliant material is selected to transmit hemodynamic pressure signals through the valve member to the pressure transducer associated with the isolation port.

6. The method of claim 2, wherein the valve member attains the open position by a reverse fluid flow generated in the isolation port.

7. The method of claim 1, wherein the inlet port is placed in fluid communication with the pressurizing device by using a fitting to connect the inlet port to the pressurizing device.

8. The method of claim 7, wherein the fitting comprises a Y-T fitting.

9. A method of protecting a pressure transducer from fluid pressure damage using a pressure isolation mechanism comprising an inlet port, an isolation port, and an internal cavity wherein a free floating, fluid flow responsive valve member is disposed and adapted to engage a seal seat in the internal cavity, and a flow initiating mechanism comprising a flow initiating member is associated with the isolation port, the method comprising:

associating the pressure transducer with the isolation port;

placing a pressurizing device for delivering fluid under pressure in fluid connection with the inlet port;

actuating the pressurizing device to cause fluid flow in the inlet port such that the free floating, fluid flow responsive valve member engages the seal seat to attain a closed position, to prevent fluid flow between the inlet port and the isolation port, and to prevent overpressure in the isolation port; and

reading hemodynamic pressure signals with the pressure transducer transmitted at least in part through a body of the valve member or a portion thereof in the closed position,

wherein the flow initiating member provides upstream volume capacitance to initiate fluid flow around the valve member such that the valve member operates to the closed position upon fluid flow initiation and operates to an open position upon fluid flow cessation.

10. The method of claim 9, further comprising deactuating the pressurizing device and allowing the upstream capacitance to act upon the valve member to attain the open position disengaged from the seal seat and permitting fluid communication between the inlet port and the isolation port.

11. The method of claim 10, further comprising reading hemodynamic pressure signals with the pressure transducer transmitted via the fluid communication between the inlet port and the isolation port in the open position of the valve member.

12. The method of claim 9, wherein the body of the valve member or a portion thereof comprises a compliant material.

13. The method of claim 12, wherein the compliant material is selected to transmit hemodynamic pressure signals through the valve member to the pressure transducer associated with the isolation port.

14. The method of claim 9, wherein the valve member attains the open position by a reverse fluid flow generated in the isolation port caused by the upstream capacitance.

15. The method of claim 9, wherein the inlet port is placed in fluid communication with the pressurizing device by using a fitting to connect the inlet port to the pressurizing device.

16. The method of claim 15, wherein the fitting comprises a Y-T fitting.

17. The method of claim 9, the pressure isolation mechanism further comprising an air inlet prevention filter disposed in a retainer retaining the flow initiating mechanism in fluid communication with the isolation port, the air inlet prevention filter adapted to prevent air from entering the internal cavity when the filter is wetted, the method further comprising:

wetting the air inlet prevention filter with fluid.

18. The method of claim 9, wherein the actuating of the pressurizing device causes the flow initiating member to compress axially to store the upstream volume capacitance.