Methods and devices for the diagnosis and treatment of diabetes
First Claim
1. A method of determining an analyte concentration within a peritoneal fluid of a human subject, comprising:
- implanting an analyte sensor apparatus in the subject, the apparatus comprising a flexible sensing catheter and a housing, the catheter comprising a lumen with at least one aperture and an analyte sensor in fluid communication with the lumen, the catheter comprising a proximal end attached to the housing, wherein the implanting step comprises positioning the sensing catheter within a true pelvis of the peritoneal space and anchoring the housing at a subcutaneous site proximate the peritoneal space;
contacting the analyte sensor with a peritoneal fluid sample outside the sensing catheter;
sensing an analyte concentration in peritoneal fluid sample; and
transducing the sensed analyte concentration into a transmittable electrical signal.
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Accused Products
Abstract
Methods and devices for the diagnosis and treatment of diabetes are disclosed in which an analyte concentration within a peritoneal fluid of a human subject may be determined by implanting an analyte sensor apparatus in the subject where the apparatus may comprise a housing and a flexible sensing catheter which has a lumen with a plurality of apertures and an exterior surface with an analyte sensor affixed thereto. The catheter may comprise a proximal end attached to the housing and the remaining end may be positioned freely within the peritoneal space to contact peritoneal fluid where an analyte concentration in the peritoneal fluid may be sensed. The housing may be anchored at a subcutaneous site proximate the peritoneal space. The sensed analyte concentration may then be transduced into a transmittable electrical signal.
81 Citations
7 Claims
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1. A method of determining an analyte concentration within a peritoneal fluid of a human subject, comprising:
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implanting an analyte sensor apparatus in the subject, the apparatus comprising a flexible sensing catheter and a housing, the catheter comprising a lumen with at least one aperture and an analyte sensor in fluid communication with the lumen, the catheter comprising a proximal end attached to the housing, wherein the implanting step comprises positioning the sensing catheter within a true pelvis of the peritoneal space and anchoring the housing at a subcutaneous site proximate the peritoneal space; contacting the analyte sensor with a peritoneal fluid sample outside the sensing catheter; sensing an analyte concentration in peritoneal fluid sample; and transducing the sensed analyte concentration into a transmittable electrical signal. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification