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Methods of using interleukin-10 for treating diseases and disorders

  • US 10,143,726 B2
  • Filed: 10/20/2015
  • Issued: 12/04/2018
  • Est. Priority Date: 10/22/2014
  • Status: Active Grant
First Claim
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1. A method of treating cancer in a human subject, comprising administering to the subject a therapeutically effective amount of an IL-10 agent, wherein the amount administered to the subject is sufficient to achieve a mean IL-10 serum trough concentration in said subject of at least the EC50 of the IL-10 agent, and wherein the serum trough concentration is maintained for at least 90% over a period of time of at least one week.

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