Isoxazole analogs as FXR agonists and methods of use thereof
First Claim
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1. A compound represented by Formula I, or a pharmaceutically acceptable salt thereof:
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Abstract
The present invention provides compounds of Formula I:
pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated as FXR modulators. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR, and methods for their preparation and use.
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20 Claims
- 1. A compound represented by Formula I, or a pharmaceutically acceptable salt thereof:
Specification