Image-based disease diagnostics using a mobile device
First Claim
1. A system for determining results for image-based disease diagnostic tests, the system comprising:
- an optical property modifying device for a nucleic acid-based disease diagnostic test, including a plurality of reaction chambers on a surface of the optical property modifying device, and configured to react a biological sample with an optical property modifying reagent, wherein a reaction within the plurality of reaction chambers modifies an optical property of the optical property modifying reagent;
a non-transitory computer readable storage medium having instructions encoded thereon that, when executed by a processor of a mobile device of a user, cause the processor to;
receive at least one image of the optical property modifying device captured by an optical sensor of the mobile device;
for each image of the at least one image, determine whether the surface of the optical property modifying device is shown in the image based on at least one of a known geometric characteristic and a known color characteristic associated with the surface of the optical property modifying device;
select one or more images of the at least one image that are determined to show the surface;
determine a test result for the nucleic acid-based disease diagnostic test based at least in part on the one or more images and at least one of the reaction chambers; and
provide the test result for display on an electronic display of the mobile device.
3 Assignments
0 Petitions
Accused Products
Abstract
A diagnostic system performs disease diagnostic tests using at least an optical property modifying device and a mobile device. A user provides a biological sample from a patient to the optical property modifying device that reacts with a reagent in one or more reaction chambers of the device. The user captures one or more images of the one or more reaction chambers using an optical sensor of the mobile device. The diagnostic system can determine a quality level of the images based on factors such as skew, scale, focusing, shadowing, or white-balancing. Based on an analysis of the captured image, the diagnostic system can determine a test result of a disease diagnostic test for the patient. The diagnostic system may communicate the test result, as well as instructions for the disease diagnostic test, to the user via the mobile device.
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Citations
30 Claims
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1. A system for determining results for image-based disease diagnostic tests, the system comprising:
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an optical property modifying device for a nucleic acid-based disease diagnostic test, including a plurality of reaction chambers on a surface of the optical property modifying device, and configured to react a biological sample with an optical property modifying reagent, wherein a reaction within the plurality of reaction chambers modifies an optical property of the optical property modifying reagent; a non-transitory computer readable storage medium having instructions encoded thereon that, when executed by a processor of a mobile device of a user, cause the processor to; receive at least one image of the optical property modifying device captured by an optical sensor of the mobile device; for each image of the at least one image, determine whether the surface of the optical property modifying device is shown in the image based on at least one of a known geometric characteristic and a known color characteristic associated with the surface of the optical property modifying device; select one or more images of the at least one image that are determined to show the surface; determine a test result for the nucleic acid-based disease diagnostic test based at least in part on the one or more images and at least one of the reaction chambers; and provide the test result for display on an electronic display of the mobile device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method comprising:
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receiving at least one image of an optical property modifying device for a nucleic acid-based disease diagnostic test captured by an optical sensor of a mobile device of a user, the optical property modifying device including a plurality of reaction chambers on a surface of the optical property modifying device and configured to react a biological sample with an optical property modifying reagent, wherein a reaction within the plurality of reaction chambers modifies an optical property of the optical property modifying reagent; for each image of the at least one image, determining whether at least one surface of the optical property modifying device is shown in the image based on at least one of a known geometric characteristic and a known color characteristic associated with the at least one surface of the optical property modifying device; selecting one or more images of the at least one image that are determined to show the at least one surface; determining a test result for the nucleic acid-based disease diagnostic test based at least in part on the one or more images and at least one of the reaction chambers; and providing the test result for display on an electronic display of the mobile device. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. A computer program product comprising a non-transitory computer readable storage medium having instructions encoded thereon that, when executed by a processor, cause the processor to:
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receive at least one image of an optical property modifying device for a nucleic acid-based disease diagnostic test captured by an optical sensor of a mobile device of a user, the optical property modifying device including a plurality of reaction chambers on a surface of the optical property modifying device and configured to react a biological sample with an optical property modifying reagent, wherein a reaction within the plurality of reaction chambers modifies an optical property of the optical property modifying reagent; for each image of the at least one image, determining whether at least one surface of the optical property modifying device is shown in the image based on at least one of a known geometric characteristic and a known color characteristic associated with the at least one surface of the optical property modifying device; select one or more images of the at least one image that are determined to show the at least one surface; determine a test result for the nucleic acid-based disease diagnostic test based at least in part on the one or more images and at least one of the reaction chambers; and provide the test result for display on an electronic display of the mobile device. - View Dependent Claims (27, 28, 29, 30)
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Specification