Method and system for image processing and patient-specific modeling of blood flow
First Claim
1. A computer-implemented method for determining patient-specific hemodynamic information using at least one computer system, the computer-implemented method comprising:
- receiving, at the at least one computer system, a patient-specific anatomic model of at least a portion of a patient'"'"'s vasculature and at least a portion of tissue supplied with blood from the portion of the patient'"'"'s vasculature;
determining, non-invasively from an estimation of blood flow through the patient-specific anatomic model by a processor of the at least one computer system, one or more first values of a blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue;
determining, non-invasively from the patient-specific anatomic model and the one or more first values of the blood flow characteristic by the processor, a first fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue;
modifying, using the at least one computer system, at least a portion of the patient-specific anatomic model to produce a modified patient-specific anatomic model, based on at least one treatment option for treating the portion of the patient'"'"'s vasculature;
determining, non-invasively from a second estimation of blood flow through the modified patient-specific anatomic model by the processor, one or more second values of the blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue;
determining, non-invasively from the modified patient-specific anatomic model and the one or more second values of the blood flow characteristic by a processor of the at least one computer system, a second fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; and
generating a visualization of one or more of the modified patient-specific anatomic model, the second fractional flow reserve value, and an assessment of the at least one treatment option based on the second fractional flow reserve value.
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Accused Products
Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient'"'"'s heart, and create a three-dimensional model representing at least a portion of the patient'"'"'s heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient'"'"'s heart and determine a fractional flow reserve within the patient'"'"'s heart based on the three-dimensional model and the physics-based model.
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Citations
22 Claims
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1. A computer-implemented method for determining patient-specific hemodynamic information using at least one computer system, the computer-implemented method comprising:
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receiving, at the at least one computer system, a patient-specific anatomic model of at least a portion of a patient'"'"'s vasculature and at least a portion of tissue supplied with blood from the portion of the patient'"'"'s vasculature; determining, non-invasively from an estimation of blood flow through the patient-specific anatomic model by a processor of the at least one computer system, one or more first values of a blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue; determining, non-invasively from the patient-specific anatomic model and the one or more first values of the blood flow characteristic by the processor, a first fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; modifying, using the at least one computer system, at least a portion of the patient-specific anatomic model to produce a modified patient-specific anatomic model, based on at least one treatment option for treating the portion of the patient'"'"'s vasculature; determining, non-invasively from a second estimation of blood flow through the modified patient-specific anatomic model by the processor, one or more second values of the blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue; determining, non-invasively from the modified patient-specific anatomic model and the one or more second values of the blood flow characteristic by a processor of the at least one computer system, a second fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; and generating a visualization of one or more of the modified patient-specific anatomic model, the second fractional flow reserve value, and an assessment of the at least one treatment option based on the second fractional flow reserve value. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A computer system for determining patient-specific hemodynamic information, the computer system comprising:
- a digital storage device storing instructions that, when executed by a processor, cause the computer system to perform a method for determining patient-specific hemodynamic information; and
a processor configured to execute the instructions to perform the method for determining patient-specific hemodynamic information, the method comprising;receiving, at the at least one computer system, a patient-specific anatomic model of at least a portion of a patient'"'"'s vasculature and at least a portion of tissue supplied with blood from the portion of the patient'"'"'s vasculature; determining, non-invasively from an estimation of blood flow through the patient-specific anatomic model by a processor of the at least one computer system, one or more first values of a blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue; determining, non-invasively from the patient-specific anatomic model and the one or more first values of the blood flow characteristic by the processor, a first fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; modifying, using the at least one computer system, at least a portion of the patient-specific anatomic model to produce a modified patient-specific anatomic model, based on at least one treatment option for treating the portion of the patient'"'"'s vasculature; determining, non-invasively from the second estimation of blood flow through the modified patient-specific anatomic model by the processor, one or more second values of the blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue; determining, non-invasively from the modified patient-specific anatomic model and the one or more second values of the blood flow characteristic by a processor of the at least one computer system, a second fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; and generating a visualization of one or more of the modified patient-specific anatomic model, the second fractional flow reserve value, and an assessment of the at least one treatment option based on the second fractional flow reserve value. - View Dependent Claims (13, 14, 15, 16, 17, 18)
- a digital storage device storing instructions that, when executed by a processor, cause the computer system to perform a method for determining patient-specific hemodynamic information; and
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19. A non-transitory computer readable medium having stored thereon a computer program comprising instructions, which, when executed by a computer, cause the computer to perform a method for determining patient-specific hemodynamic information, the method comprising:
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receiving, at the at least one computer system, a patient-specific anatomic model of at least a portion of a patient'"'"'s vasculature and at least a portion of tissue supplied with blood from the portion of the patient'"'"'s vasculature; determining, non-invasively from an estimation of blood flow through the patient-specific anatomic model by a processor of the at least one computer system, one or more first values of a blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue; determining, non-invasively from the patient-specific anatomic model and the one or more first values of the blood flow characteristic by the processor, a first fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; modifying, using the at least one computer system, at least a portion of the patient-specific anatomic model to produce a modified patient-specific anatomic model, based on at least one treatment option for treating the portion of the patient'"'"'s vasculature; determining, non-invasively from a second estimation of blood flow through the modified patient-specific anatomic model by processor, one or more second values of the blood flow characteristic within the portion of the patient'"'"'s vasculature or the portion of tissue; determining, non-invasively from the modified patient-specific anatomic model and the one or more second values of the blood flow characteristic by a processor of the at least one computer system, a second fractional flow reserve value that indicates a risk of low blood flow to the portion of tissue; and generating a visualization of one or more of the modified patient-specific anatomic model, the second fractional flow reserve value, and an assessment of the at least one treatment option based on the second fractional flow reserve value. - View Dependent Claims (20, 21, 22)
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Specification