System and method for cardiac valve repair and replacement

• US 10,149,761 B2
• Filed: 08/28/2017
• Issued: 12/11/2018
• Est. Priority Date: 07/17/2013
• Status: Active Grant

• Current Assignee: Cephea Valve Technologies, Inc. (Abbott Laboratories)
• Original Assignee: Cephea Valve Technologies, Inc. (Abbott Laboratories)
• Inventors: Granada, Juan F., Erzberger, Gary, Corcoran, Michael P., Wallace, Dan, Montorfano, Matteo, Chieffo, Alaide
• Primary Examiner(s): Gherbi, Suzette J
• Application Number:
  US15/688,701
• Publication Number:
  US 20170354499A1
• Time in Patent Office: 470 Days
• Field of Search: 623 21- 219
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2439 Expansion controlled by filaments
• CPC Class Codes: A61F 2002/9665 with additional retaining means
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped

Abstract

A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween.

Claims

1. A prosthetic mitral valve comprising:

an anchor assembly comprising a ventricular anchor, a central portion, and an atrial anchor, the anchor assembly configured to self-expand from a collapsed configuration to an expanded configuration;

a plurality of struts attached to the anchor assembly;

a plurality of leaflets secured to the plurality of struts; and

a plurality of retention hooks attached to the ventricular anchor, wherein each of the retention hooks curves radially outwards when the anchor assembly is in the expanded configuration and flattens when the anchor assembly is in the collapsed configuration, and wherein the plurality of struts and plurality of leaflets extend distally past the retention hooks when the anchor assembly is in the expanded configuration.

2. The prosthetic mitral valve of claim 1, wherein the plurality of retention hooks are attached only to the ventricular anchor.

3. The prosthetic mitral valve of claim 1, wherein the plurality of retention hooks are made of nitinol.

4. The prosthetic mitral valve of claim 1, wherein the plurality of retention hooks are integral with the anchor assembly.

5. The prosthetic mitral valve of claim 1, wherein at least a portion of the anchor assembly is covered with a skirt configured to seal the prosthetic mitral valve during use.

6. The prosthetic mitral valve of claim 1, wherein the plurality of leaflets comprise a biomaterial.

7. The prosthetic mitral valve of claim 1, wherein the plurality of leaflets are arranged to fill an inner diameter of the prosthetic mitral valve.

8. The prosthetic mitral valve of claim 1, wherein the ventricular anchor and the atrial anchor are configured to flare outward relative to the central portion when self-expanding from the collapsed configuration to the expanded configuration.

9. The prosthetic mitral valve of claim 1, wherein the ventricular anchor and the atrial anchor are both formed of a plurality of arcuate portions.

10. A prosthetic mitral valve comprising:

an anchor assembly comprising a ventricular anchor, a central portion, and an atrial anchor, the anchor assembly configured to expand from a collapsed configuration to an expanded configuration;

a plurality of replacement leaflets secured to the anchor assembly; and

a plurality of retention hooks attached only to the ventricular anchor, wherein each of the retention hooks curves radially outwards when the anchor assembly is in the expanded configuration and flattens when the anchor assembly is in the collapsed configuration, and wherein the plurality of leaflets extend distally past the retention hooks when the anchor assembly is in the expanded configuration.

11. The prosthetic mitral valve of claim 10, wherein the anchor assembly is configured to self-expand from the collapsed configuration to the expanded configuration.

12. The prosthetic mitral valve of claim 10, wherein the plurality of retention hooks are made of nitinol.

13. The prosthetic mitral valve of claim 10, wherein the plurality of retention hooks are integral with the anchor assembly.

14. The prosthetic mitral valve of claim 10, wherein at least a portion of the anchor assembly is covered with a skirt configured to seal the prosthetic mitral valve during use.

15. The prosthetic mitral valve of claim 10, further comprising a plurality of struts attached to the anchor assembly, the plurality of leaflets secured to the anchor assembly with the plurality of struts.

16. The prosthetic mitral valve of claim 10, wherein the plurality of leaflets comprise a biomaterial.

17. The prosthetic mitral valve of claim 10, wherein the plurality of leaflets are arranged to fill an inner diameter of the prosthetic mitral valve.

18. The prosthetic mitral valve of claim 10, wherein the ventricular anchor and the atrial anchor are configured to flare outward relative to the central portion when expanding from the collapsed configuration to the expanded configuration.

19. The prosthetic mitral valve of claim 10, wherein the ventricular anchor and the atrial anchor are both formed of a plurality of arcuate portions.