Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly

• US 10,149,943 B2
• Filed: 05/29/2015
• Issued: 12/11/2018
• Est. Priority Date: 05/29/2015
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: Bar-El, Yossi, Yigal, Gil, Filman, Reuven Y.
• Primary Examiner(s): Farrar, Lauren P
• Application Number:
  US14/725,009
• Publication Number:
  US 20160346478A1
• Time in Patent Office: 1,292 Days
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/31505 Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31576 Constructional features or modes of drive mechanisms for piston rods

Abstract

A cartridge interface assembly drives a stopper in a drug reservoir or a drug delivery device. An anti-rotational guide optionally moves along an axis of a cavity of the reservoir. The anti-rotational guide is optionally slidably anti-rotationally coupled to a housing of the drug delivery device. A telescoping plunger driver may include a proximal shaft and distal shaft that telescope by relative rotation. The distal shaft is optionally slidably anti-rotationally coupled to the anti-rotational guide. The shafts are optionally oriented along said axis. In some embodiments, rotating the proximal shaft with respect to the anti-rotational guide moves the guide along said axis with respect to the housing and moves the distal shaft along the axis with respect to the anti-rotational guide.

Claims

1. An assembly for driving a stopper in a drug reservoir of a drug delivery device, the assembly comprising:

an anti-rotational stabilizer anti-rotationally coupled to a housing of the drug delivery device;

a stopper adapter configured to engage the stopper of the drug reservoir;

a telescoping assembly that telescopes by relative rotation between at least a proximal shaft and a distal shaft oriented along an axis of said reservoir;

the proximal shaft being linearly stabilized by a shoulder bearing of the anti-rotational stabilizer, said shoulder bearing preventing movement of said proximal shaft in a proximal direction with respect to the anti-rotational stabilizer while permitting rotation of said proximal shaft with respect to the anti-rotational stabilizer and the distal shaft being in engagement with the stopper adapter; and

;

anti-rotational guides including telescoping posts anti-rotationally extending between the anti-rotational stabilizer and the stopper adapter,

wherein rotating said proximal shaft with respect to said anti-rotational stabilizer moves said distal shaft and said stopper adapter along said axis, thereby slidably expanding the anti-rotational telescoping posts.

2. The assembly of claim 1, further comprising:

an intermediate shaft threadably engaged to said proximal shaft and to said distal shaft such that said telescoping assembly also telescopes by rotating said proximal shaft with respect to said intermediate shaft.

3. The assembly of claim 2, wherein a maximum axial movement of said distal shaft with respect to the reservoir is greater than a maximum axial movement of said intermediate shaft with respect to the reservoir.

4. The assembly of claim 1, wherein said anti-rotational guides include a guide track.

5. An assembly for driving a stopper in a drug reservoir of a drug delivery device, the assembly comprising:

a telescoping assembly that telescopes by relative rotation between at least a proximal shaft and a distal shaft oriented along an axis of said reservoir;

said distal shaft configured to engage the stopper of the drug reservoir;

an anti-rotational guide sized to move along said axis of the reservoir;

said anti-rotational guide slidably and anti-rotationally coupled to a housing of the drug delivery device;

a coupling slidably and anti-rotationally linking said anti-rotational guide to said distal shaft;

said sliding and anti-rotation with respect to said axis of the reservoir such that rotating said proximal shaft with respect to said anti-rotational guide moves said distal shaft along said axis and moves said distal shaft with respect to said anti-rotational guide, said anti-rotational guide also moving along said axis;

a linear stabilizer coupled to said proximal shaft, inhibiting axial movement of said proximal shaft in a proximal direction with respect to said linear stabilizer, said linear stabilizer coupled to the reservoir inhibiting axial movement of said linear stabilizer in a proximal direction with respect to the reservoir, such that said rotation of said proximal shaft causes said distal shaft to advance distally inside of the drug reservoir,

wherein said linear stabilizer includes an anti-rotational connector fitting to said housing for preventing rotation of said linear stabilizer with respect to said housing and wherein said anti-rotational guide slidably engages to said housing by means of said linear stabilizer.

6. The assembly of claim 5, wherein the anti-rotational connector is also shaped to attach to a proximal portion of said reservoir.

7. The assembly of claim 6, wherein said anti-rotational connector is shaped to attach to a flange of said reservoir.

8. The assembly of claim 5, wherein said reservoir and said assembly form a cartridge and wherein said housing includes an opening fitting said cartridge and wherein said anti-rotational connector is shaped to connect to said housing to limit rotation of said anti-rotational connector with respect to said housing when said cartridge is inserted into said opening.

9. The assembly of claim 5, further comprising:

a bearing preventing proximal movement of said proximal shaft with respect to said housing and allowing rotation of said proximal shaft with respect to said housing.