Catheter-assisted tumor treatment
First Claim
1. A method for treating a subject diagnosed with a cancer, comprising:
- advancing an implant to a target region of a body lumen which is near or contains the cancer, the implant having first and second sections engaged with a catheter at respective first and second engagement points;
releasing the implant first section from engagement with the catheter at the first engagement point;
permitting the implant first section to expand against a lumen wall at the target region such that the lumen becomes at least substantially occluded; and
injecting a therapeutic material through a portion of the implant while the implant second section remains unexpanded and engaged with the catheter, wherein the material is effective to treat the cancer.
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Accused Products
Abstract
A method for treating a subject diagnosed with a cancer or other disorder comprising a hyperproliferative tissue is described herein. The method includes localized delivery of a material which contains a therapeutically effective agent and/or moiety. The localized delivery of the agent is achieved using a catheter-based delivery system and an implant. An implant can include a support component, a cover component, and a valve component. The valve component can be operable to permit flow through the implant. The implant can be delivered on a catheter, with one of the ends of the implant being selectively expanded to permit temporary occlusion of a vessel while delivering a material through the valve component to a downstream target region. The other end of the implant can thereafter be released such that the implant occludes the vessel, or the implant can be removed from the vessel entirely.
434 Citations
14 Claims
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1. A method for treating a subject diagnosed with a cancer, comprising:
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advancing an implant to a target region of a body lumen which is near or contains the cancer, the implant having first and second sections engaged with a catheter at respective first and second engagement points; releasing the implant first section from engagement with the catheter at the first engagement point; permitting the implant first section to expand against a lumen wall at the target region such that the lumen becomes at least substantially occluded; and injecting a therapeutic material through a portion of the implant while the implant second section remains unexpanded and engaged with the catheter, wherein the material is effective to treat the cancer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification