Renal therapy system with cassette-based blood and dialysate pumping

• US 10,155,080 B2
• Filed: 02/05/2018
• Issued: 12/18/2018
• Est. Priority Date: 11/05/2003
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Lo, Ying-Cheng, Childers, Robert W., Kelly, Thomas D., Rohde, Justin
• Primary Examiner(s): Mensh, Andrew J
• Application Number:
  US15/888,566
• Publication Number:
  US 20180169316A1
• Time in Patent Office: 316 Days
• Field of Search: 604 609, 604 501
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1563 Details of incorporated filters
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1603 Regulation parameters
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1635 with volume chamber balancing devices between used and fresh dialysis fluid
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/3401 Cassettes therefor
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/36224 : with sensing means or components thereof
• CPC Class Codes: A61M 1/36225 : with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 : at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362262 : Details of incorporated reservoirs
• CPC Class Codes: A61M 1/362265 : Details of valves
• CPC Class Codes: A61M 1/3627 : Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 2205/127 : with provisions for heating or cooling
• CPC Class Codes: A61M 2205/3331 : Pressure; Flow
• CPC Class Codes: A61M 2205/3368 : Temperature
• CPC Class Codes: A61M 2205/502 : User interfaces, e.g. screens or keyboards
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

A renal therapy system with cassette-based blood and dialysate pumping is disclosed. An example system includes a blood pump actuator, a dialysis fluid pump actuator, a dialysis fluid heater, a dialyzer, and a disposable unit. The example disposable unit includes a blood cassette portion configured to be operatively connected to the blood pump actuator to pump blood through the blood cassette portion. The example disposable unit also includes a dialysis fluid cassette portion, separate from the blood cassette portion, configured to be operatively connected to the dialysis fluid pump actuator to pump dialysis fluid through the dialysis fluid cassette portion. The blood cassette portion and the dialysis fluid cassette portion are both in fluid communication with the dialyzer. The example disposable unit also includes a heater bag configured to be placed in operable communication with the dialysis fluid heater and in fluid communication with the dialysis fluid cassette portion.

Claims

1. A renal therapy system comprising:

a peristaltic blood pump actuator;

a peristaltic dialysis fluid pump actuator;

a dialysis fluid heater;

a dialyzer; and

a disposable unit including

a blood cassette portion including a blood cassette housing and configured to be operatively connected to the peristaltic blood pump actuator to pump blood through the blood cassette portion when the blood cassette portion is in fluid communication with a blood source, the blood cassette portion in fluid communication with the dialyzer and including an air separation chamber for separating air from the pumped blood,

a dialysis fluid cassette portion including a dialysis fluid cassette housing separate from the blood cassette housing and configured to be operatively connected to the peristaltic dialysis fluid pump actuator to pump dialysis fluid through the dialysis fluid cassette portion when the dialysis fluid cassette portion is in fluid communication with a dialysis fluid source, the dialysis fluid cassette portion in fluid communication with the dialyzer, and

a heater bag configured to be placed in operable communication with the dialysis fluid heater and in fluid communication with the dialysis fluid cassette portion via a to-heater tube and a from-heater tube, wherein the heater bag is spaceable away from the dialysis fluid cassette portion, and wherein the dialysis fluid heater is spaced away from the peristaltic dialysis fluid pump actuator so that the heater bag is placeable in operable communication with the dialysis fluid heater while the dialysis fluid cassette portion is operably connected to the peristaltic dialysis fluid pump actuator.

2. The renal therapy system of claim 1, which includes a renal therapy machine including (i) the peristaltic blood pump actuator located at a blood pump portion of the machine operable with the blood cassette portion of the disposable unit, (ii) the peristaltic dialysis fluid pump actuator located at a dialysis fluid pump portion of the machine operable with the dialysis fluid cassette portion of the disposable unit, and (iii) the dialysis fluid heater located at a heater portion of the machine operable with the heater bag of the disposable unit.

3. The renal therapy system of claim 2, wherein the heater portion of the machine is located between the dialysis fluid pump portion of the machine and the blood pump portion of the machine.

4. The renal therapy system of claim 2, wherein the dialysis fluid pump portion of the machine is located between the heater portion of the machine and the blood pump portion of the machine.

5. The renal therapy system of claim 2, wherein the heater bag in operation is placed between the heater portion of the machine and a door hinged to the machine.

6. The renal therapy system of claim 5, wherein the heater bag is positioned vertically between the heater portion of the machine and the door.

7. The renal therapy system of claim 1, wherein the air separation chamber is in fluid communication with a from-dialyzer line.

8. The renal therapy system of claim 1, wherein the air separation chamber is in fluid communication with a to-patient line.

9. The renal therapy system of claim 1, wherein the blood cassette housing is integrated with the dialysis fluid cassette housing.

10. The renal therapy system of claim 1, wherein the blood cassette housing is located at a first side of the disposable unit and the dialysis fluid cassette housing is located at a second side of the disposable unit.

11. A renal therapy system comprising:

a peristaltic blood pump actuator;

a peristaltic dialysis fluid pump actuator;

a dialysis fluid heater;

a dialyzer; and

a disposable unit including

a blood cassette portion configured to be operatively connected to the peristaltic blood pump actuator to pump blood through the blood cassette portion when the blood cassette portion is in fluid communication with a blood source, the blood cassette portion in fluid communication with the dialyzer and having a blood cassette housing,

a dialysis fluid cassette portion configured to be operatively connected to the peristaltic dialysis fluid pump actuator to pump dialysis fluid through the dialysis fluid cassette portion when the dialysis fluid cassette portion is in fluid communication with a dialysis fluid source, the dialysis fluid cassette portion in fluid communication with the dialyzer and having a dialysis cassette housing separate from the blood cassette housing, and

a heater bag configured to be placed in operable communication with the dialysis fluid heater and in fluid communication with the dialysis fluid cassette portion via a to-heater tube and a from-heater tube, the to-heater tube in fluid communication with the from-heater tube via a serpentine heating pathway provided within the heater bag, wherein the heater bag is spaceable away from the dialysis fluid cassette portion, and wherein the dialysis fluid heater and the peristaltic blood pump actuator are spaced away from the peristaltic dialysis fluid pump actuator so that (i) the heater bag is placeable in operable communication with the dialysis fluid heater while the dialysis fluid cassette portion is operably connected to the peristaltic dialysis fluid pump actuator and (ii) the blood cassette housing in operation is spaced away from the dialysis fluid cassette housing.

12. The renal therapy cassette of claim 11, wherein the dialysis fluid cassette portion includes at least one dialysis fluid pumping tube connected to the dialysis fluid cassette housing for operation with the dialysis fluid pump actuator.

13. The renal therapy cassette of claim 11, wherein the blood cassette portion includes at least one blood pumping tube connected to the blood cassette housing for operation with the peristaltic blood pump actuator.

14. The renal therapy cassette of claim 13, wherein the blood pumping tube extends outside the blood cassette housing.

15. The renal therapy cassette of claim 11, wherein at least one of the blood cassette housing and the dialysis fluid cassette housing is formed from a hard plastic.

16. The renal therapy cassette of claim 11, wherein the blood cassette housing includes a to-dialyzer tube port and a from-dialyzer tube port.

17. A disposable unit for a renal therapy system, the disposable unit comprising:

a blood cassette portion including a blood cassette housing and a blood pumping tube;

a dialysis fluid cassette portion including a dialysis fluid cassette housing separate from the blood cassette housing, a dialysis fluid pumping tube, a to-heater tube and a from-heater tube; and

a heater bag in fluid communication with the to-heater tube and the from-heater tube via a serpentine heating pathway located within the heater bag.

18. The disposable unit of claim 17, wherein the heater bag is structured to communicate with the to-heater tube along a same side of the heater bag as the from-heater tube.

19. The disposable unit of claim 17, wherein the dialysis fluid pumping tube of the dialysis fluid cassette portion is a fresh dialysis fluid pumping tube for pumping fresh dialysis fluid to a dialyzer, and wherein the dialysis fluid cassette portion includes a used dialysis fluid pumping tube for pumping effluent dialysis fluid from the dialyzer.

20. The disposable unit of claim 17, wherein the blood cassette portion of the disposable unit includes a fluid passageway dedicated to accepting an auxiliary fluid different than blood.