Positioning a medical device based on oxygen saturation measurements

• US 10,165,969 B2
• Filed: 04/27/2015
• Issued: 01/01/2019
• Est. Priority Date: 01/06/2015
• Status: Active Grant

• Current Assignee: LifeWatch Technologies Ltd. (Koninklijke Philips N.V.)
• Original Assignee: Braemar Incorporated
• Inventors: Levant, Anna, Halevi, Zohar Brachia, Amirim, Mordehay
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Liu, Chu Chuan (JJ)
• Application Number:
  US14/696,523
• Publication Number:
  US 20160192868A1
• Time in Patent Office: 1,345 Days
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/6823 Trunk, e.g., chest, back, abdomen, hip
• CPC Class Codes: A61B 5/721 using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence

Abstract

A method that includes receiving first and second detection signals and electrocardiograph signals; wherein the first detection signals result from an illumination, by an oxygen saturation sensor included in a device that may be removably attached to a user, of a sternal angle of a user by infrared pulses; wherein the second detection signals result from an illumination, by the oxygen saturation sensor, of the sternal angle of a user by visible light pulses; wherein the electrocardiograph signals may be detected by an electrocardiography sensor that may be included in the device; generating a first waveform template that may be responsive to the first detection signals; generating a second waveform template that may be responsive to the second detection signals; calculating an indication of the oxygen saturation characteristic of the user in response to the first and second detection signals; detecting cardiac cycle durations that may be based upon the first and second detection signals; detecting electrocardiography based cardiac cycle durations; and evaluating a quality of the indication of the oxygen saturation characteristic of the user in response to the first waveform template, the second waveform template, the cardiac cycle'"'"'s durations and the electrocardiography based cardiac cycle durations.

Claims

1. A method for measuring oxygen saturation of a user, the method comprises:

receiving, by a computerized device, first and second detection signals and electrocardiograph signals;

wherein the first detection signals result from an illumination by infrared pulses of a sternal angle of a user, and being detected by an oxygen saturation sensor included in a device that is removably attached to a user;

wherein the second detection signals result from an illumination by visible light pulses detected by the oxygen saturation sensor, of the sternal angle of a user;

wherein the electrocardiograph signals are detected by an electrocardiography sensor that is included in the device;

generating a first waveform template by analyzing the second detection signals to normalize the second detection signals and identify cardiac cycle duration characteristics of the second detection signals that are substantially consistent within the second detection signals;

calculating an indication of the oxygen saturation characteristic of the user in response to the first and second detection signals;

detecting cardiac cycle durations that are based upon the first and second detection signals;

detecting electrocardiography based cardiac cycle durations; and

evaluating a quality of the indication of the oxygen saturation characteristic of the user by comparing the first waveform template to the electrocardiography based cardiac cycle durations.

2. The method according to claim 1 comprising applying a high-pass filter and a bilateral filter on the first detection signals to provide first filtered detection signals.

3. The method according to claim 1 wherein the generating of the first waveform template comprises filtering the first detection signals to provide first filtered detection signals;

and detecting first cardiac cycle waveforms in the first filtered detection signals.

4. The method according to claim 3 wherein the detecting of the cardiac cycle durations comprises measuring durations of the first cardiac cycle waveforms.

5. The method according to claim 3 wherein the generating of the first waveform template comprises converting the first cardiac cycle waveforms to first duration-normalized cardiac cycle waveforms that have a same duration.

6. The method according to claim 5 wherein the generating of the first waveform template is responsive to at least some of the first duration-normalized cardiac cycle waveforms.

7. The method according to claim 5 wherein the generating of the first waveform template equals an average of at least some of the first duration-normalized cardiac cycle waveforms.

8. The method according to claim 5 wherein the generating of the first waveform template further comprises calculating, for each first duration-normalized cardiac cycle waveform, a similarity score indicative of a similarity between the first duration-normalized cardiac cycle waveform and other first duration-normalized cardiac cycle waveforms.

9. The method according to claim 8 wherein the generating of the first waveform template further comprises ignoring at least one first duration-normalized cardiac cycle waveform based upon similarity scores of the first duration-normalized cardiac cycle waveforms.

10. The method according to claim 8 wherein the calculating, for each first duration-normalized cardiac cycle waveform, of the similarity score comprises calculating a plurality of Pearson correlation coefficients between the first duration-normalized cardiac cycle waveform and a plurality of other first duration-normalized cardiac cycle waveforms.

11. The method according to claim 10 wherein the calculating, for each first duration-normalized cardiac cycle waveform, of the similarity score comprises summing the plurality of Pearson correlation coefficients.

12. The method according to claim 3 comprising calculating qualities of at least some of the first cardiac cycle waveforms;

and wherein the quality of the first and second detection signals is responsive to the qualities of the at least some of the first cardiac cycle waveform.

13. The method according to claim 12 wherein the calculating of the qualities of at least some of the first cardiac cycle waveforms comprises comparing the at least some of the first cardiac cycle waveforms to the first waveform template.

14. The method according to claim 12 wherein the calculating of the qualities of at least some of the first cardiac cycle waveforms comprises calculating correlations between shapes of the at least some of the first cardiac cycle waveforms and a shape of the first waveform template.

15. The method according to claim 12 wherein the calculating of the qualities of at least some of the first cardiac cycle waveforms comprises converting at least some of the first cardiac cycle waveforms to first duration-normalized and peak-normalized cardiac cycle waveforms and a shape of the first waveform template;

and wherein the first duration-normalized and peak-normalized cardiac cycle waveforms are a same duration and a same peak value as the first waveform template.

16. The method according to claim 12 wherein the calculating of the qualities of at least some of the first cardiac cycle waveforms comprises calculating relationships between peaks of the at least some of the first cardiac cycle waveforms and a peak of the first waveform template.

17. A non-transitory computer readable medium that stores instructions that once executed by a computerized device cause the computerized device to execute the steps of:

receiving first and second detection signals and electrocardiograph signals;

wherein the first detection signals result from an illumination by infrared pulses of a sternal angle of a user, and being detected by an oxygen saturation sensor included in a device that is removably attached to a user;

wherein the second detection signals result from an illumination by visible light pulses detected by the oxygen saturation sensor, of the sternal angle of a user;

wherein the electrocardiograph signals are detected by an electrocardiography sensor that is included in the device;

generating a first waveform template that is responsive to the first detection signals;

generating a second waveform template that is responsive to the second detection signals;

calculating an indication of the oxygen saturation characteristic of the user in response to the first and second detection signals;

detecting cardiac cycle durations that are based upon the first and second detection signals;

detecting electrocardiography based cardiac cycle durations using an electrocardiography sensor; and

evaluating a quality of the indication of the oxygen saturation characteristic of the user by comparing the first waveform template, and the second waveform template to the cardiac cycle'"'"'s durations and to the electrocardiography based cardiac cycle durations.

18. A medical device that comprises a processor that is configured to receive first and second detection signals and electrocardiograph signals and having an illumination source for generating infrared and visible light pulses and having an electrocardiograph sensor for detecting electrocardiography based cardiac cycle durations;

wherein the first detection signals result from an illumination by infrared pulses, by an oxygen saturation sensor included in the device which is removably attached to a user, of a sternal angle of a user;

wherein the second detection signals result from an illumination, by the oxygen saturation sensor, of the sternal angle of a user;

wherein the electrocardiograph signals may be detected by the electrocardiography sensor included in the device;

(ii) generate a first waveform template responsive to the first detection signals;

(iii) generate a second waveform template responsive to the second detection signals;

(iv) calculate an indication of the oxygen saturation characteristic of the user in response to the first and second detection signals;

(v) detect cardiac cycle durations based upon the first and second detection signals;

(vi) using the electrocardiography sensor detect electrocardiography based cardiac cycle durations; and

(vii) evaluate a quality of the indication of the oxygen saturation characteristic of the user in response to comparing the first waveform template, and the second waveform template to the cardiac cycle'"'"'s durations and to the electrocardiography based cardiac cycle durations.