Personalized detection system for detecting magnetic objects in the human organism

• US 10,165,988 B2
• Filed: 06/06/2014
• Issued: 01/01/2019
• Est. Priority Date: 06/20/2013
• Status: Active Grant

• Current Assignee: Evonik Operations GmbH (Rag-Stiftung)
• Original Assignee: Evonik Rã¶Hm GmbH (Rag-Stiftung)
• Inventors: Hartwig, Benedikt, Niepoth, Peter, Stiller, Hans-Joachim, Junginger, Steffen
• Primary Examiner(s): Cattungal, Sanjay
• Application Number:
  US14/899,400
• Publication Number:
  US 20160135759A1
• Time in Patent Office: 1,670 Days
• Field of Search: 600407-430, 324318-322
• CPC Class Codes: A61B 2562/0223 Magnetic field sensors
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/4205 Evaluating swallowing
• CPC Class Codes: A61B 5/6804 Garments; Clothes
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61J 3/007 Marking tablets or the like apparatus for printing on tablets or the like B41F17/36
• CPC Class Codes: G01R 33/096 anisotropic magnetoresistance sensors
• CPC Class Codes: G01V 3/081 the magnetic field is produced by the objects or geological structures characterised by the method of magnetic field measurement G01R33/00

Abstract

The invention relates to a device with a sensor arrangement, which is able to detect magnetic or magnetized oral administration forms after oral take-up, moreover tracks the dissolution thereof via the reduction or disappearance of the magnetic field of the oral administration form, and with a log function, which records a subjective evaluation on the part of the human wearer of the sensor arrangement during or after the oral take-up.

Claims

1. A device, comprising

a detector system for registering magnetic bodies in the human organism, which detector system comprises:

at least two sensor arrangements with an instrument for recording the magnetic flux density measured by each sensor arrangement, wherein each sensor arrangement has one, two or three anisotropic magnetoresistance sensors, the axes of easy magnetization of which point in pair-wise different directions, and each sensor arrangement has a distance of 0.5 to 50 cm from the remaining sensor arrangement or sensor arrangements, and at least two sensor arrangements are tilted at an angle of between 0 and 45°

with respect to one another, and

a log for registering a quantified evaluation before, during and/or after the registration of the magnetic body or bodies.

2. The device according to claim 1, wherein

the sensor arrangements are integrated in at least one strap, the clothing and/or an item of jewelry, or worn or affixed directly on the body by means of a suction cup or fastening aid, and

the log is carried on the body.

3. The device according to claim 1, wherein the log is a mobile computer, a mobile telephone, PDA, small computer, data logger with transmitter, and/or an input unit, and the log is electronically connected to the sensor arrangement.

4. A method for registering the magnetic flux density generated by a magnetic body in the human organism by means of a device according to claim 1, comprising:

(a) applying a set and reset pulse, at least once, to each

anisotropic magnetoresi stance sensor,

(b) amplifying the signals of each AMR sensor by means of suitable

signal conditioning and by means of at least one low-pass filter,

(c) determining and recording the difference in the magnitudes of the vectors of the magnetic flux densities of each sensor arrangement,

and/or

determining and recording the angle Φ

between the vectors from the measurement signals of the AMR sensors,

and,

(d) simultaneously with one of the steps (a), (b) or (c) or

after a time T has elapsed following step (c),

registering the quantified evaluation, at least once, in the log, which is undertaken by the human wearer of the sensor arrangements.

5. The method according to claim 4, wherein the quantified evaluation is undertaken by virtue of the fact that a sense of well-being and/or physical fitness and/or at least one other subjective criterion, is assigned to alphanumerical signs or a grade scale, and entered into the log.

6. The method according to claim 5, wherein the values, obtained in step (c), for the difference

and/or for the angle Φ

are recorded as a function of time and the evaluation, registered in step (d), is recorded as a function of time.

7. A method for registering oral administration forms and determining the time or times of the disintegration of the magnetic component in the digestive tract comprising registering magnetic bodies in a human organism with the device according to claim 1.

8. The method according to claim 7, wherein the measurement signals obtained are stored in a data storage device, and the stored data are optionally, upon reception of a request signal, transmitted to a receiving device.

9. A data management network comprising the device according to claim 1.

10. The method according to claim 7 wherein said human organism is in need of therapy and/or nutrition.