Sphingosine kinase type 1 inhibitors and uses thereof
First Claim
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1. A method for treating ulcerative colitis in a patient, comprising:
- administering to a patient in need of treatment for ulcerative colitis a compound having the formula
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Abstract
Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (GBM).
19 Citations
18 Claims
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1. A method for treating ulcerative colitis in a patient, comprising:
administering to a patient in need of treatment for ulcerative colitis a compound having the formula - View Dependent Claims (2, 3)
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4. A method for treating ulcerative colitis in a patient, comprising:
administering to a patient in need of treatment for ulcerative colitis a compound having the formula - View Dependent Claims (5, 6, 7, 8, 9)
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10. A method for treating colon cancer in a patient, comprising:
administering to a patient in need of treatment for colon cancer a compound having the formula - View Dependent Claims (11, 12)
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13. A method for treating colon cancer in a patient, comprising:
administering to a patient in need of treatment for colon cancer a compound having the formula - View Dependent Claims (14, 15, 16, 17, 18)
Specification