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Automatic closed-loop control adjustments and infusion systems incorporating same

  • US 10,166,331 B2
  • Filed: 06/21/2016
  • Issued: 01/01/2019
  • Est. Priority Date: 02/06/2014
  • Status: Active Grant
First Claim
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1. A method of operating an infusion device comprising a motor operable to deliver a fluid to a user, the method comprising:

  • identifying a condition of the user that is likely to influence a response to the fluid in a body of the user;

    classifying the condition as exercise; and

    after classifying the condition as exercise;

    estimating an amount of energy expenditure during the exercise;

    calculating a change in glycemic level for the user based on the amount of energy expenditure;

    determining an equivalent insulin amount based on the change in glycemic level;

    determining an adjusted proportional gain coefficient based on a first difference between a daily insulin requirement for the user and the equivalent insulin amount;

    determining a delivery command by applying the adjusted proportional gain coefficient to a second difference between a measured glucose value obtained from a glucose sensing arrangement and a target blood glucose; and

    operating the motor of the infusion device in accordance with the delivery command to deliver the fluid to the user in accordance with the adjusted proportional gain coefficient.

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