Intracorporeal marker and marker delivery device

• US 10,172,674 B2
• Filed: 06/20/2013
• Issued: 01/08/2019
• Est. Priority Date: 02/02/1999
• Status: Expired due to Fees

• Current Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Original Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Inventors: Jones, Michael L., Lubock, Paul, Merritt, John
• Primary Examiner(s): Park, Patricia
• Assistant Examiner(s): Mehl, Patrick M
• Application Number:
  US13/922,860
• Publication Number:
  US 20130281847A1
• Time in Patent Office: 2,028 Days
• Field of Search: 600431
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00637 for sealing trocar wounds through abdominal wall
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 2090/3987 Applicators for implanting markers
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

An intracorporeal marker system includes a tissue marker pellet comprised of a polysaccharide material. The intracorporeal marker system may also include a fibrous marker of bioabsorbable fibers. In one embodiment, for example, an outer layer of bioabsorbable fibers is disposed around at least part of an inner core of bioabsorbable fibers.

Claims

1. An intracorporeal marker system, comprising:

an elongated intracorporeal marker having an inner core of bioabsorbable fibers and an outer layer of bioabsorbable fibers disposed around at least part of the inner core; and

a tissue marker pellet comprised of a polysaccharide material.

2. The intracorporeal marker system of claim 1, comprising a plurality of polysaccharide marker pellets.

3. The intracorporeal marker system of claim 1, comprising:

an elongated tubular shaft which has a distal end, a proximal end, an inner lumen extending between the proximal end and the distal end, and a distal discharge opening, wherein each of the elongated intracorporeal marker and the tissue marker pellet being disposed in the inner lumen prior to delivery to a delivery site in a patient; and

a plunger element slidably disposed in part within the inner lumen of the elongated tubular shaft proximal to each of the elongated intracorporeal marker and the tissue marker pellet.

4. A remotely imageable breast tissue marker system, comprising:

an elongated tubular shaft which has a distal end, a proximal end, an inner lumen extending between the proximal end and the distal end, and a distal discharge opening;

a proximal breast tissue marker comprised of a polysaccharide slidably disposed in the inner lumen of the elongated tubular shaft, the proximal breast tissue marker comprised of polysaccharide configured to exhibit hemostatic properties;

a fibrous breast tissue marker comprising bioabsorbable fibers slidably disposed in the inner lumen of the elongated tubular shaft at a location distal to the proximal breast tissue marker comprised of polysaccharide; and

a plunger element which is slidably disposed in part within the inner lumen of the elongated tubular shaft proximal to the proximal breast tissue marker comprised of polysaccharide, and which is configured to discharge in sequence the fibrous breast tissue marker and the proximal breast tissue marker comprised of polysaccharide from the distal discharge opening of the elongated tubular shaft.

5. The remotely imageable breast tissue marker system of claim 4, comprising a plurality of polysaccharide breast tissue marker elements disposed in the inner lumen of the elongated tubular shaft.

6. The remotely imageable breast tissue marker system of claim 4, comprising at least one bioactive component selected from the group consisting of therapeutic and diagnostic agents.

7. A remotely imageable breast tissue marker system comprising:

a breast tissue marker pellet comprised of a polysaccharide configured to exhibit hemostatic properties;

a fibrous breast tissue marker comprising bioabsorbable fibers; and

a delivery tube having an inner lumen, and wherein the fibrous breast tissue marker is interposed in the inner lumen between two polysaccharide breast tissue marker pellets.

8. The remotely imageable breast tissue marker system of claim 7, comprising a radiopaque element coupled with at least one of the polysaccharide breast tissue marker pellets and the fibrous breast tissue marker.

9. A remotely imageable breast tissue marker system comprising:

a breast tissue marker pellet comprised of a polysaccharide configured to exhibit hemostatic properties; and

a fibrous breast tissue marker comprising bioabsorbable fibers, wherein the fibrous breast tissue marker comprises a multi-layered breast tissue marker having an inner core of bioabsorbable fibers and an outer layer of bioabsorbable fibers disposed around the inner core, and having a radiopaque marker element disposed around the multi-layered breast marker that is configured to constrict the multi-layered breast tissue marker.