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Methods, medical devices and kits for modifying the luminal profile of a body vessel

  • US 10,173,027 B2
  • Filed: 10/07/2016
  • Issued: 01/08/2019
  • Est. Priority Date: 10/07/2015
  • Status: Active Grant
First Claim
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1. A method of modifying the luminal profile of a body vessel of an animal, comprising:

  • advancing a cannula out of the distal end of a catheter disposed within the lumen of said body vessel and toward a target site on the wall of said body vessel;

    passing contrast dye through the cannula toward the target site;

    simultaneously continuing the advancing and passing until the distal end of the cannula punctures the inner layer of the wall of said body vessel at the target site; and

    passing a bulking agent through the cannula and into a space between connective tissue layers surrounding the vessel wall at the target sitefurther comprising passing a crosslinking agent through the cannula and into the space between connective tissue layers surrounding the vessel wall at the target site;

    wherein the passing a crosslinking agent through the cannula and into the space between connective tissue layers surrounding the vessel wall at the target site is performed before the step of passing a bulking agent through the cannula and into a space between connective tissue layers surrounding the vessel wall at the target site.

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