Microplate and methods for making the same
First Claim
1. A method for making a microplate comprising:
- providing a carrier including a plate with a top face, a bottom face spaced from the top face in a direction, and an annular perimeter, with the plate including an array of through-holes extending from the top face through the bottom face and located inside the annular perimeter, with the array of holes terminating at the top face and at the bottom face, with the bottom face being substantially planar;
providing a flexible tape piece made of a single piece of material, with the flexible tapepiece including an upper surface and a lower surface spaced a thickness from the upper surface in the direction, with the flexible tape piece further including an array of closed wells, the closed wells configured and arranged to receive and store assay samples, and wherein each wellis integrally extending in the direction away from the upper and lower surfaces and each having an open end comprising an opening extending from the upper surface into the well and a closed end comprising an integral bottom spaced from the open end, with the openings of the array of wells having sizes generally corresponding to the array of through-holes of the plate, with at least a portion of the array of wells having a number and locations generally corresponding to the array of holes of the plate, with the carrier formed of material more rigid than the material forming the flexible tape piece; and
abutting and bonding at least a portion of the upper surface of the tape with at least a portion of the bottom face of the plate so that at least a portion of the openings of the array of wells generally correspond to the array of holes of the plate.
3 Assignments
0 Petitions
Accused Products
Abstract
A microplate (10) includes a carrier (12) having a plate (20) and an annular perimeter wall (30) to define a recess (34). An array of holes (26) extends through the plate (20). A tape piece (16), die cut from a flexible tape (60) includes an array of wells (54) each extending through and having an opening (56) extending into the well (54). The array of wells (54) has a number and locations corresponding to the array of holes (26). The openings (56) have sizes corresponding to the holes (26). An upper surface (50) of the tape piece (16) is abutted with and bonded to the bottom face (24) of the plate (20) with the openings (56) corresponding to the array of holes (26). The slideable receipt of an annular outer periphery (58) of the tape piece (16) insures that the array of wells (54) are aligned to correspond to the array of holes (26) as die cutting of tape piece (16) insures that the array of wells (54) are at consistent positions relative to the annular outer periphery (58).
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Citations
19 Claims
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1. A method for making a microplate comprising:
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providing a carrier including a plate with a top face, a bottom face spaced from the top face in a direction, and an annular perimeter, with the plate including an array of through-holes extending from the top face through the bottom face and located inside the annular perimeter, with the array of holes terminating at the top face and at the bottom face, with the bottom face being substantially planar; providing a flexible tape piece made of a single piece of material, with the flexible tape piece including an upper surface and a lower surface spaced a thickness from the upper surface in the direction, with the flexible tape piece further including an array of closed wells, the closed wells configured and arranged to receive and store assay samples, and wherein each well is integrally extending in the direction away from the upper and lower surfaces and each having an open end comprising an opening extending from the upper surface into the well and a closed end comprising an integral bottom spaced from the open end, with the openings of the array of wells having sizes generally corresponding to the array of through-holes of the plate, with at least a portion of the array of wells having a number and locations generally corresponding to the array of holes of the plate, with the carrier formed of material more rigid than the material forming the flexible tape piece; and abutting and bonding at least a portion of the upper surface of the tape with at least a portion of the bottom face of the plate so that at least a portion of the openings of the array of wells generally correspond to the array of holes of the plate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14)
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11. A method for making a microplate comprising:
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providing a carrier including a plate with a top face, a bottom face spaced from the top face in a direction, and an annular perimeter, with the plate including an array of through-holes extending from the top face through the bottom face and located inside the annular perimeter, with the array of holes terminating at the top face and at the bottom face, with the bottom face being substantially planar; cutting a tape piece as a single piece including an upper surface and a lower surface spaced a thickness from the upper surface in the direction, with the tape piece as cut further including an array of wells, the wells being closed wells that are configured and arranged to each receive samples and/or reagents and to store samples, and wherein the wells each integrally extend in the direction away from the upper and lower surfaces and each having an open end comprising an opening extending from the upper surface into the well and a closed end comprising an integral bottom spaced from the opening, with the openings of the array of wells having sizes generally corresponding to the array of holes of the plate, with the array of wells having a number and locations generally corresponding to the array of holes of the plate, with the carrier formed of material more rigid than material forming the single piece; and abutting and bonding at least a portion of the upper surface to at least a portion of the bottom face of the plate with the openings of the array of wells generally corresponding to the array of holes of the plate. - View Dependent Claims (15, 16, 17, 18, 19)
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Specification