Bi-hemispheric brain wave system and method of performing bi-hemispherical brain wave measurements

• US 10,178,952 B2
• Filed: 03/15/2013
• Issued: 01/15/2019
• Est. Priority Date: 01/12/2011
• Status: Active Grant

• Current Assignee: T&W Engineering A/S (WS Audiology A/S)
• Original Assignee: Widex A/S (WS Audiology A/S)
• Inventors: Westermann, Soren Erik, Kidmose, Preben, Rank, Mike Lind, Ungstrup, Michael
• Primary Examiner(s): Cheng, Jacqueline
• Assistant Examiner(s): PORTILLO, JAIRO H
• Application Number:
  US13/838,351
• Publication Number:
  US 20130184552A1
• Time in Patent Office: 2,132 Days
• Field of Search: None
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/374 Detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
• CPC Class Codes: A61B 5/38 Acoustic or auditory stimuli
• CPC Class Codes: A61B 5/6817 Ear canal
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

A system (100) for bi-hemispheric brain wave measurements including a first device (102) and a second device (103), wherein at least said first device (102) is adapted to be worn in or at a first ear of a person subject to the measurements and wherein the first (102) and second (103) device exchange data using a wireless link (104). The invention also provides a method for measuring a bi-hemispherical brain wave signal.

Claims

1. A system for bi-hemispheric brain wave measurements, comprising:

a first device configured to be worn in or at a first ear of a person subject to the measurements and comprising a first and a second measurement electrode adapted for measuring a first brain wave signal, a first data acquisition component coupled to said measurement electrodes, said first data acquisition component comprising at least one amplifier and configured to provide first digital data representing said first brain wave signal, a first brain wave signal analyzer configured for analyzing at least said first digital data, and first wireless link component operable to establish a wireless connection with a second wireless link component; and

a second device configured to be worn in or at a second ear of said person and comprising a third and a fourth measurement electrode adapted for measuring a second brain wave signal, a second data acquisition component coupled to said measurement electrodes, said second data acquisition component comprising at least one amplifier and configured to provide second digital data representing said second brain wave signal, and said second wireless link component;

wherein said first brain wave signal analyzer is configured to combine a first characteristic feature and second characteristic feature during the course of its analysis, wherein the first characteristic feature is derived unilaterally from the first device of the system and the second characteristic feature is derived unilaterally from the second device of the system, wherein the system is configured for detection of at least one of impending hypoglycemia or epileptic seizures based said analysis by said first brain wave signal analyzer, and redundancy from having a combination of unilateral signal features is provided to improve robustness of said system.

2. The system according to claim 1, wherein at least one of said first and said second device of said system comprises a first part implanted subcutaneously outside the skull of said person and a second part adapted to be carried behind the ear of said person, wherein said first part comprises the measurement electrodes of at least one of said first and said second device.

3. The system according to claim 2, wherein said second part includes said first wireless link component as well as a further wireless link component configured to establish a wireless link between said first and second parts.

4. The system according to claim 3, wherein each of said first and second devices includes a further wireless link component for establishing a wireless connection with an external device.

5. The system according to claim 1, wherein at least one of said first and said second device of said system is adapted to be worn at least partly within an ear canal of said person, and wherein the measurement electrodes of at least one of said first and said second device comprise at least two surface electrodes adapted to be placed in said ear canal.

6. The system according to claim 5, wherein at least one of said first and said second device of said system comprises a shell, wherein the contours of the outer surface of said shell and said measurement electrodes are individually matched to at least part of said ear canal.

7. The system according to claim 6, wherein each of said first and second devices is configured to be positioned completely within a respective ear of said person, each of said first and second devices comprising a shell having outer surface contours individually matched to at least part of the respective ear canal, with contact surfaces of said measurement electrodes also individually matched to said part of said respective ear canal.

8. The system according to claim 1, comprising a fifth electrode adapted for attachment to the scalp of said person, hereby providing a third brain wave signal.

9. The system according to claim 8 comprising a connector for providing a detachable connection between said fifth electrode and said first or said second device of the system.

10. The system according to claim 1, wherein said first brain wave signal analyzer is configured to derive a characteristic feature of a brain wave signal based on an analysis method selected from a group consisting of time-frequency analysis, time-domain analysis and data-driven signal decomposition.

11. The system according to claim 10, wherein said first brain wave signal analyzer is configured to combine a first brain wave signal from the first device with a second brain wave signal from the second device and to derive a characteristic feature based on the two signals, whereby a bilateral signal feature is provided.

12. The system according to claim 1, wherein said first brain wave signal analyzer is configured to combine a first characteristic feature and a second characteristic feature, using a method selected from a group consisting of difference, ratio, correlation, coherence, higher order moments and conditional expectations.

13. The system according to claim 1, wherein said system comprises a first speaker, and wherein said wireless connection provides co-ordination between said first and said second device such that a brain wave measurement can be performed based on a contra-lateral auditory stimulation by said first speaker.

14. The system according to claim 13, wherein said brain wave measurement provides a measurement of an auditory brainstem response.

15. The system according to claim 13, wherein said first speaker is accommodated in said first device, and a second speaker is accommodated in said second device, wherein said first device is adapted to provide a first auditory signal that is frequency shifted relative to a second auditory signal provided by said second device, whereby a binaural beat is provided to the user.

16. The system according to claim 1, wherein each of said first and second devices is configured to be positioned completely within a respective ear canal of said person.

17. The system according to claim 1, wherein each of said first and second devices includes a further wireless link component for establishing a wireless connection with an external device.

18. The system according to claim 1, wherein the second device includes a second brain wave signal analyzer that is configured in the same way as the first brain wave signal analyzer.

19. The system according to claim 1, wherein said first brain wave signal analyzer includes:

a feature extractor for extracting features from said first digital data and from said second digital data, including said first and second characteristic features; and

a classifier responsive to the extracted features and generating a class vector representing a classification of said extracted features.

20. A method for performing bi-hemispherical brain wave analysis, comprising the steps of:

measuring a first brain wave at a first device in, or in the vicinity of, a first ear of a person subject to the analysis;

measuring a second brain wave at a second device in, or in the vicinity of, a second ear of said person;

wirelessly transmitting data representing at least one of said first and said second measured brain wave using a wireless connection between said first device and said second device; and

analyzing data representing said first and said second measured brain wave, hereby providing a bi-hemispherical brain wave analysis;

wherein said analyzing step comprises combining a first characteristic feature and second characteristic feature, wherein the first characteristic feature is derived unilaterally from the first device and the second characteristic feature is derived unilaterally from the second device, wherein the method comprises detection of at least one of impending hypoglycemia or epileptic seizures based on results of said analyzing, and redundancy from having a combination of unilateral signal features is provided to improve robustness of said method.

21. The method according to claim 20, comprising the steps of providing a first audio stimulation of the first ear of said person, providing a second audio stimulation of the second ear of said person, and synchronizing in time said first and second audio stimulation hereby providing binaural audio stimulation.

22. The method according to claim 20, wherein the brain wave analysis is conducted by a signal processor located within one of said first and second devices.

23. A method for performing bi-hemispherical brain wave analysis, comprising the steps of:

providing from a first device an audio stimulation of a first ear of a person subject to an analysis;

measuring a brain wave at a second device in, or in the vicinity of, a second ear of said person;

exchanging data over a wireless connection between said first and second devices in order to synchronize in time said first and said second device;

analyzing said brain wave measurement with respect to the audio stimulation;

wherein said analyzing step comprises combining a first characteristic feature and second characteristic feature, wherein the first characteristic feature is derived unilaterally from the first device and the second characteristic feature is derived unilaterally from the second device, wherein the method comprises detection of at least one of impending hypoglycemia and epileptic seizures based on said analyzing, and redundancy from having a combination of unilateral signal features is provided to improve robustness of said detection.

24. The method according to claim 23, wherein said brain wave measurement and a contra-lateral audio stimulation are synchronized in time.

25. The method according to claim 24, wherein said brain wave measurement provides an auditory evoked brainstem response.

26. The method according to claim 24, wherein said brain wave measurement provides an EEG measurement.

27. The method according to claim 23, wherein said analyzing step is conducted by a signal processor located within one of said one of said first and second devices.