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Methods of transplanting chondrocytes

  • US 10,179,193 B2
  • Filed: 01/16/2018
  • Issued: 01/15/2019
  • Est. Priority Date: 10/29/2012
  • Status: Active Grant
First Claim
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1. A method of treating a bone or cartilage defect in a subject in need thereof, comprising administering a transplantation composition at a site of the bone or cartilage defect, the transplantation composition comprising:

  • a) a tri-component matrix, consisting of;

    i) isolated and purified non-denatured type II collagen at a concentration of 0.5 mg/ml to 5 mg/ml;

    ii) hyaluronan at a concentration of 1 mg/ml to 3 mg/ml; and

    iii) chondroitin sulfate at a concentration of 0.25 mg/ml to 3 mg/ml; and

    b) water; and

    c) a population of cells.

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