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Method comprising contacting tissue with a cross-linkable polyester prepolymer

  • US 10,179,195 B2
  • Filed: 02/17/2014
  • Issued: 01/15/2019
  • Est. Priority Date: 01/12/2006
  • Status: Active Grant
First Claim
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1. A polyester composition comprising a plurality of polyester polymeric backbones of general formula (-A-B—

  • )n, comprising A and B components, wherein n is an integer greater than 1, and wherein the polymeric backbones are formed by reaction of;

    the A component which is a compound having two or more —

    OR groups wherein each R is independently selected from hydrogen or an alkyl group; and

    the B component which is a diacid compound;

    wherein one or more of the —

    OR groups within the polyester polymeric backbones is functionalized with a vinyl-containing moiety prior to crosslinking;

    wherein crosslinking the vinyl-containing moieties within the polyester polymeric backbones forms crosslinks between the plurality of the polyester polymeric backbones, the crosslinks containing a dioic acid ester functionality,wherein the polyester composition when crosslinked is an adhesive elastomeric polymer, andwherein the polyester composition when crosslinked is non-toxic to humans, biocompatible, and bioabsorbable.

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