Lead for an active implantable medical device with a chip for electrode multiplexing

• US 10,182,730 B2
• Filed: 04/24/2015
• Issued: 01/22/2019
• Est. Priority Date: 12/14/2010
• Status: Active Grant

• Current Assignee: Sorin CRM USA (MicroPort Scientific Corp.)
• Original Assignee: Sorin CRM USA (MicroPort Scientific Corp.)
• Inventors: Ollivier, Jean-Francois
• Primary Examiner(s): Cohen, Lee S
• Assistant Examiner(s): Cardinal, Erin M
• Application Number:
  US14/696,064
• Publication Number:
  US 20150223713A1
• Time in Patent Office: 1,369 Days
• CPC Class Codes: A61B 2562/125 characterised by the manufacture of electrodes
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/125 objective methods
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0587 Epicardial electrode systems; Endocardial electrodes piercing the pericardium
• CPC Class Codes: H01R 43/20 for assembling or disassembling contact members with insulating base, case or sleeve
• CPC Class Codes: Y10S 439/909 Medical use or attached to human body
• CPC Class Codes: Y10T 29/49146 with encapsulating, e.g., potting, etc.
• CPC Class Codes: Y10T 29/49169 Assembling electrical component directly to terminal or elongated conductor
• CPC Class Codes: Y10T 29/49171 with encapsulating

Abstract

A lead for active implantable medical devices comprising a chip, notably for electrode multiplexing. The lead includes an insulating supporting tube interposed in a flexible elongated tube, with a central bore coaxial with the lumen of the lead. The supporting tube comprises on its surface at least one crossing conductive strip extending in the axial direction. A chip on a flexible substrate is disposed with a bent or curved conformation in a receptacle of the supporting tube isolated from the conductive strip. An electrode, e.g., for cardiac sensing/pacing, carried by the supporting tube is electrically connected to an outer conductive pad of the chip. The conductive strip is connected (i) at each end, face to face to a conductive connection, housed in the sheath, and (ii) in a central region, to an inner conductive pad of the chip.

Claims

1. A lead for an active implantable medical device, comprising:

an elongated flexible sheath having a central lumen and at least one conductive connection housed in the central lumen of the sheath;

wherein the elongated flexible sheath and the at least one conductive connection are separated into two or more segments by at least one rigid supporting tube interposed in the sheath, the two or more segments comprising a first segment and a second segment, the supporting tube comprising;

a central region and two end regions, wherein the central region has a diameter that is greater than a diameter of the two end regions;

wherein the central region further comprises a cavity, the cavity forming a chip receptacle;

a chip held in the chip receptacle comprising a substrate and further comprising a first conductive contact pad and a second conductive contact pad;

an electrode positioned on the supporting tube such that the first conductive contact pad of the chip is connected to the electrode; and

a conductive strip formed on an outer surface of the supporting tube and extending in an axial direction along a length of the supporting tube, wherein the conductive strip comprises a central portion and two end portions, wherein the second conductive contact pad on the chip is connected to the conductive strip, and wherein a first of the two end portions of the conductive strip is electrically coupled to the first segment of the at least one conductive connection and a second of the two end portions of the conductive strip is electrically coupled to the second segment of the at least one conductive connection.

2. The lead of claim 1, wherein the electrode includes a conductive sleeve circumferentially extending around a periphery of the central region of the supporting tube.

3. The lead of claim 1, wherein the first conductive contact pad is positioned on an exterior surface of the substrate of the chip and the second conductive contact pad is positioned on an interior surface of the substrate of the chip.

4. The lead of claim 3, wherein the chip has a thickness that corresponds with a depth of the cavity such that the exterior surface of the chip is flush with the diameter of the central region of the supporting tube.

5. The lead of claim 3, wherein the substrate of the chip is flexible such that the interior surface of the chip forms to the outer surface of the supporting tube when the chip is held in the chip receptacle.

6. The lead of claim 1, wherein the supporting tube comprises at least one of a ceramic material and a plastic material that electrically isolates the supporting tube.

7. The lead of claim 1, wherein the conductive strip is a first conductive strip, the lead further comprising a second conductive strip, wherein the first conductive strip and the second conductive strip are disposed on diametrically opposed regions of the supporting tube.

8. The lead of claim 1, further comprising an insulating sleeve that defines a plurality of cavities and circumferentially extends around a periphery of the central region of the supporting tube, wherein the electrode comprises a plurality of sector electrodes, one of each of the plurality of sector electrodes disposed with each of the plurality of cavities, wherein the first conductive contact pad comprises a plurality of first conductive contact pads, and wherein each of the plurality of sector electrodes is connected to a corresponding one of the plurality of first conductive contact pads of the chip.

9. The lead of claim 1, wherein the cavity is formed on an outer surface of the central region of the supporting tube.

10. A supporting tube of a lead for an active implantable medical device, comprising:

a conductive strip disposed on an outer surface of the supporting tube and extending in an axial direction along a length of the supporting tube and including a central portion and two end portions, wherein a first of the two end portions of the conductive strip is configured to be electrically coupled to a first segment of an at least one conductive connection and a second of the two end portions is configured to be electrically coupled to a second segment of the at least one conductive connection; and

a central region and two end regions, the central region extending from the outer surface of the supporting tube such that the central region has a diameter greater than the two end regions and defining a cavity, the cavity forming a chip receptacle structured to hold a chip;

wherein the chip includes an interior contact pad and an exterior contact pad, the conductive strip configured to contact the interior contact pad of the chip.

11. The supporting tube of claim 10, further comprising a conductive sleeve configured as an electrode and circumferentially extending around a periphery of the central region of the supporting tube.

12. The supporting tube of claim 11, wherein the conductive sleeve is structured to contact the exterior contact pad of the chip when the chip is held in the receptacle.

13. The supporting tube of claim 10, further comprising an insulating sleeve defining a plurality of cavities and circumferentially extending around a periphery of the central region of the supporting tube.

14. The supporting tube of claim 13, wherein the supporting tube is configured to couple with a chip having a plurality of exterior contact pads, and wherein each of the plurality of cavities of the insulating sleeve is configured to correspond with one of the plurality of exterior contact pads when the chip is held in the receptacle.

15. The supporting tube of claim 14, further comprising a plurality of electrodes, wherein one of the plurality of electrodes is disposed within each of the plurality of cavities such that each of the plurality of electrodes is contacting one of the plurality of exterior contact pads of the chip when the chip is held in the receptacle.

16. The supporting tube of claim 10, wherein the cavity has a depth configured to correspond to a thickness of the chip, such that the diameter of the central region of the supporting tube is flush with an exterior surface of the chip when the chip is held in the receptacle.

17. The supporting tube of claim 10, wherein the supporting tube is shaped such that an interior surface of the supporting tube forms to the interior surface of the chip when the chip is held in the chip receptacle.

18. The supporting tube of claim 10, wherein the conductive strip is a first conductive strip, the lead further comprising a second conductive strip, wherein the first conductive strip and the second conductive strip are disposed on diametrically opposed regions of the supporting tube.

19. The supporting tube of claim 18, wherein the supporting tube is configured to couple with a chip having a first interior contact pad and a second interior contact pad, and wherein the first conductive strip is configured to contact the first interior contact pad and the second conductive strip is configured to contact the second interior contact pad when the chip is held in the receptacle.

20. The supporting tube of claim 10, wherein the cavity is formed on an outer surface of the central region of the supporting tube.