Multisignal reagents for labeling analytes
First Claim
1. A multisignal labeling reagent comprising:
- a first polymer covalently bound to(a) a reactive group or a first member of a first binding pair, and(b) more than one digoxigenin molecule; and
bound to each digoxigenin molecule, an anti-digoxigenin antibody that is further bound to at least one signal molecule.
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Accused Products
Abstract
Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. Additionally provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule.
45 Citations
23 Claims
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1. A multisignal labeling reagent comprising:
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a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule; and bound to each digoxigenin molecule, an anti-digoxigenin antibody that is further bound to at least one signal molecule. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification