Locating J-points in electrocardiogram signals

• US 10,188,305 B2
• Filed: 06/30/2016
• Issued: 01/29/2019
• Est. Priority Date: 07/09/2015
• Status: Active Grant

• Current Assignee: Dragerwerk AG & Company KGaA (FPS Vermögensverwaltung GmbH)
• Original Assignee: Dragerwerk AG & Company KGaA (FPS Vermögensverwaltung GmbH)
• Inventors: Zhang, Zhe, Roset, Scott, Chen, Yu
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Piateski, Erin M
• Application Number:
  US15/199,036
• Publication Number:
  US 20170007144A1
• Time in Patent Office: 943 Days
• Field of Search: 600521
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence

Abstract

The current subject matter determines the location of the J-point in an ECG signal by examining ECG samples within a window of samples between the S-peak and the T-peak. The sample in this range with the smallest distance, Δd, to the R-peak is selected as the J-point. Thus, the J-point location can be determined based on an ECG sample'"'"'s distance to the R-peak. The J-point location can then be used to determine whether there is elevation or depression of the ST segment. Related apparatus, systems, techniques, and articles are also described.

Claims

1. A method for locating a J-point in a cardiac cycle waveform, the method being implemented by one or more data processors forming part of at least one computing device, the method comprising:

receiving electrocardiogram (ECG) data derived from an ECG electrode set affixed to a patient, the ECG data comprising a sequence of cardiac cycle waveforms that each correspond to a single cardiac cycle, each waveform comprising a series of samples;

locating, for each cardiac cycle waveform, an R-peak, an S-peak, and a T-peak;

calculating, for each cardiac cycle waveform, a Euclidian distance between the R-Peak and each of a plurality of samples within a window of samples;

locating a J-point for each cardiac cycle waveform by identifying, as a location of the J-point in the cardiac cycle waveform, a sample from among the plurality of samples having the shortest Euclidian distance to the R-peak; and

determining a physical state of the patient based on the J-point located in at least one cardiac cycle waveform.

2. The method of claim 1, further comprising:

calculating, for each cardiac cycle waveform, a midpoint sample between the S-peak and the T-peak;

wherein the window only includes samples between the S-peak and the midpoint sample.

3. The method of claim 1, further comprising:

identifying, for each cardiac cycle waveform, beginning of a T wave corresponding to the T-peak; and

measuring, for each cardiac cycle waveform, a deviation of an ST segment starting at the J-point and terminating at the beginning of the T wave relative to a baseline, the ST segment corresponding to an interval between ventricular depolarization and repolarization of the patient.

4. The method of claim 3, wherein the baseline is a PR interval of the corresponding cardiac cycle waveform defined by an end of a P wave and start of a QRS complex in the cardiac cycle waveform.

5. The method of claim 3, further comprising:

providing data characterizing the measured deviation of the ST segment.

6. The method of claim 5, wherein providing data characterizing the measured deviation of the ST segment comprises at least one of:

displaying at least a portion of the data on an electronic display, loading at least a portion of the data into memory, storing at least a portion of the data into persistent storage, or transmitting at least a portion of the data to a remote computing system.

7. The method of claim 3, wherein the measured deviation is an elevation of the ST segment relative to the baseline or a depression of the ST segment relative to the baseline.

8. The method of claim 1 further comprising:

scaling, prior to the calculating, each cardiac cycle waveform to a predetermined scale.

9. The method of claim 8, wherein each cardiac cycle waveform is scaled such that, on an x-axis of the cardiac cycle waveform, the scaling is between the R-peak and a midpoint sample between the S-peak and the T-peak and, on a y-axis of the cardiac cycle waveform, the scaling is between.

10. The method of claim 1, further comprising:

providing, for each cardiac cycle waveform, data specifying the location of the identified J-point for the cardiac cycle waveform,

wherein the providing data comprises at least one of;

displaying at least a portion of the data on an electronic display, loading at least a portion of the data into memory, storing at least a portion of the data into persistent storage, or transmitting at least a portion of the data to a remote computing system.

11. The method of claim 1, wherein at least one of the receiving, the locating the R-peak, the S-peak, and the T-peak, the calculating, the locating the J-point, and the determining is executed by a patient monitor in communication with the ECG electrode set.

12. The method of claim 1, wherein the ECG data is continuously updated while the patient is being monitored.

13. The method of claim 1, wherein in the calculating, the Euclidian distance between the R-Peak and each of the plurality of samples is calculated using the following equation:

d=√

{square root over ((x₂−

x₁)²++(y₂−

y₁)²)}

where d is the Euclidian distance,

(x₁,y₁) are coordinates of the R-peak, and

(x₂, y₂) are coordinates of the sample.

14. A system for locating a J-point in a cardiac cycle waveform, the system comprising:

at least one data processor; and

memory storing instructions which, when executed by the at least one data processor, perform operations comprising;

receiving electrocardiogram (ECG) data derived from an ECG electrode set affixed to a patient, the ECG data comprising a sequence of cardiac cycle waveforms that each correspond to a single cardiac cycle, each waveform comprising a series of samples;

locating, for each cardiac cycle waveform, an R-peak, an S-peak, and a T-peak;

calculating, for each cardiac cycle waveform, a Euclidian distance between the R-Peak and each of a plurality of samples within a window of samples;

locating a J-point for each cardiac cycle waveform by identifying, as a location of the J-point in the cardiac cycle waveform, a sample from among the plurality of samples having the shortest Euclidian distance to the R-peak; and

determining a physical state of the patient based on the J-point located in at least one cardiac cycle waveform.

15. The system of claim 14 further comprising:

an electrocardiogram (ECG) electrode set for generating ECG signals when affixed to a patient.

16. The system of claim 15, wherein the at least one data processor and memory form part of a patient monitor, the patient monitor comprising an interface for communication with the ECG electrode set.

17. A non-transitory computer program product storing instructions which, when executed by at least one data processor forming part of at least one computing device, perform operations for locating a J-point in a cardiac cycle waveform, the operations comprising:

receiving electrocardiogram (ECG) data derived from an ECG electrode set affixed to a patient, the ECG data comprising a sequence of cardiac cycle waveforms that each correspond to a single cardiac cycle, each waveform comprising a series of samples;

locating, for each cardiac cycle waveform, an R-peak, an S-peak, and a T-peak;

calculating, for each cardiac cycle waveform, a Euclidian distance between the R-Peak and each of a plurality of samples within a window of samples;

locating a J-point for each cardiac cycle waveform by identifying, as a location of the J-point in the cardiac cycle waveform, a sample from among the plurality of samples having the shortest Euclidian distance to the R-peak; and

determining a physical state of the patient based on the J-point located in at least one cardiac cycle waveform.