Mechanism for preventing selection of a dose

• US 10,188,801 B2
• Filed: 08/11/2011
• Issued: 01/29/2019
• Est. Priority Date: 08/13/2010
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Butler, Joseph, Avery, Richard James Vincent
• Primary Examiner(s): Lee, Brandy S
• Application Number:
  US13/813,477
• Publication Number:
  US 20130218095A1
• Time in Patent Office: 2,728 Days
• Field of Search: 604207, 604209
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge

Abstract

A dose setting mechanism having a locking mechanism for preventing selection of a dose in a drug delivery device is disclosed. The dose setting mechanism includes a locking mechanism that prevents movement of the dose setting mechanism. When a correct cartridge is inserted into the drug delivery device, the locking mechanism unlocks so as to allow movement of the dose setting mechanism. In one arrangement, the locking mechanism prevents rotation of the dose setting mechanism.

Claims

1. A dose setting mechanism for use with a drug delivery device, the dose setting mechanism comprising:

a dose setter for selecting a dose; and

a locking mechanism configured to prevent movement of the dose setter and selection of the dose,

wherein the locking mechanism is configured such that inserting a correct cartridge into the drug delivery device unlocks the locking mechanism so as to allow movement of the dose setter and selection of the dose, and

wherein the locking mechanism is configured such that inserting an incorrect cartridge into the drug delivery device locks the locking mechanism so as to prevent the dose setter from setting a dose, wherein the locking mechanism prevents the dose setter from rotating, and wherein, when the correct cartridge is inserted into the drug delivery device, the locking mechanism unlocks so as to allow the dose setter to rotate.

2. The dose setting mechanism of claim 1, wherein the correct cartridge comprises a coded cartridge that unlocks the locking mechanism, or wherein a coded cartridge holder unlocks the locking mechanism.

3. The dose setting mechanism of claim 2, wherein the coded cartridge comprises a protrusion.

4. The dose setting mechanism according to claim 1, wherein the locking mechanism comprises at least one locking element and at least one protrusion, wherein the at least one locking element moves in a proximal direction to unlock the locking mechanism.

5. The dose setting mechanism according to claim 1, wherein the locking mechanism comprises at least one locking pin and a gear, wherein the at least one locking pin moves in a distal direction to unlock the locking mechanism.

6. The dose setting mechanism according to claim 1, wherein the locking mechanism comprises a first and a second locking arm provided on a pivoting hub, wherein the locking arms are configured to bend as the hub pivots.

7. The dose setting mechanism according to claim 1, wherein the locking mechanism comprises a locking arm.

8. The dose setting mechanism of claim 7, wherein the locking arm comprises a pivotable locking arm configured to interact with a groove located on the dose setting mechanism.

9. The dose setting mechanism of a claim 7, wherein the locking arm is positioned in a circumferential direction.

10. A drug delivery system, the system comprising:

a drug delivery device comprising the dose setting mechanism according to claim 1, wherein the locking mechanism of the dose setting mechanism is configured to prevent a movement of the dose setter of the dose setting mechanism.

11. The drug delivery system of claim 10, further comprising a cartridge holder secured to the dose setting mechanism, a cartridge being contained within the cartridge holder, and the cartridge holder having a coding that unlocks the locking mechanism.

12. The drug delivery system according to claim 10, wherein the coding comprises a protrusion.

13. The drug delivery system according to claim 10, wherein the drug delivery system comprises a reusable drug delivery system or a non-reusable drug delivery system.

14. The drug delivery system according to claim 10, wherein the drug delivery system further comprises a cartridge contained within the dose setting mechanism.

15. A dose setting mechanism for use with a drug delivery device, the dose setting mechanism comprising:

a body

a dose setter for selecting a dose; and

a locking mechanism configured to prevent movement of the dose setter and selection of the dose,

wherein the locking mechanism comprises a movable locking element supported by the body, mechanically engageable with the dose setter, and movable between a first position and a second position, wherein, when in the first position, the movable locking element prevents the dose setter from rotating relative to the body, and wherein when the movable locking element is in the second position the dose setter is free to rotate relative to the body, and

wherein the locking mechanism is configured such that inserting a correct cartridge into the drug delivery device moves the movable locking element from the first position into the second position to unlock the locking mechanism and to allow movement of the dose setter and selection of the dose.

16. The dose setting mechanism according to claim 15, wherein the locking mechanism is configured such that inserting an incorrect cartridge into the drug delivery device keeps the movable locking element in the first position.

17. The dose setting mechanism according to claim 15, further comprising a spring configured to bias the movable locking element in the first position.

18. The dose setting mechanism according to claim 15, further comprising a movable locking ring comprising a locking ring coding and connected to the movable locking element, the locking ring being movable relative to the body between a distal position and a proximal position such that the movable locking element is in the first position when the locking ring is in the distal position and such that the movable locking element is in the second position when the locking ring is in the proximal position.

19. The dose setting mechanism according to claim 18, wherein the locking ring is configured to be moved from the distal axial position into the proximal axial position only by a cartridge coding matching with the locking ring coding.

20. A drug delivery system, the system comprising:

a drug delivery device comprising the dose setting mechanism according to claim 15, wherein the locking mechanism of the dose setting mechanism is configured to prevent a movement of the dose setter of the dose setting mechanism.