Systems and methods for tissue stimulation in medical treatment
First Claim
1. A neurostimulation system, comprising:
- at least one electrical lead configured for being implanted in a patient and coupled to a plurality of electrical contacts;
a control subsystem having control circuitry configured for;
controlling a stimulation subsystem having stimulation circuitry for generating a plurality of individual partial signals which are electrical pulse trains at one or more pulse rates, and the control circuitry is configured for instructing a modulation output circuitry to repeatedly generate the plurality of individual electrical pulse trains that result in a vector field having a bursting pattern;
routing the pulse trains from the stimulation circuitry to the plurality of electrical contacts; and
,concurrently conveying each of the plurality of electrical pulse trains respectively to at least one of the plurality of electrical contacts in a manner that allows a combined vector electrical pulse train to be characterized by a pulse rate for at least a portion of the vector electrical pulse train that is equal to or greater than twice the frequency of the individual pulse trains,wherein at least one electrical pulse train has a frequency of between 1 kHz and 100 kHz.
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Abstract
Stimulation treatments for various medical disorders, such as neurological disorders, comprise novel systems, strategies, and methods for providing TMS, electrical, magnetic, optical and other stimulation. Some stimulation methods comprise varying the stimulation parameters to improve the therapeutic efficacy of stimulation, and decrease risk of habituation and side-effects such as interference with normal brain, sensory, motor, and cognitive processes. The creation, and subsequent variation, of stimulation parameters can use sensed data in order to match, adjust, or avoid matching characteristics of the stimulation therapy relative to certain endogenous brain activities. Novel methods are described for choosing, creating and subsequently stimulating with partial signals which summate to produce therapeutic vector fields having unique temporal patterns and low- or high-frequency spectral content.
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Citations
19 Claims
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1. A neurostimulation system, comprising:
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at least one electrical lead configured for being implanted in a patient and coupled to a plurality of electrical contacts; a control subsystem having control circuitry configured for; controlling a stimulation subsystem having stimulation circuitry for generating a plurality of individual partial signals which are electrical pulse trains at one or more pulse rates, and the control circuitry is configured for instructing a modulation output circuitry to repeatedly generate the plurality of individual electrical pulse trains that result in a vector field having a bursting pattern; routing the pulse trains from the stimulation circuitry to the plurality of electrical contacts; and
,concurrently conveying each of the plurality of electrical pulse trains respectively to at least one of the plurality of electrical contacts in a manner that allows a combined vector electrical pulse train to be characterized by a pulse rate for at least a portion of the vector electrical pulse train that is equal to or greater than twice the frequency of the individual pulse trains, wherein at least one electrical pulse train has a frequency of between 1 kHz and 100 kHz. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A neurostimulation system, comprising:
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at least one electrical lead configured for being implanted in a patient and coupled to a plurality of electrical contacts; a control subsystem having control circuitry configured for; controlling a stimulation subsystem having stimulation circuitry for generating a plurality of individual partial signals which are electrical pulse trains at one or more pulse rates; routing the pulse trains from the stimulation circuitry to the plurality of electrical contacts; and
,concurrently conveying each of the plurality of electrical pulse trains respectively to at least one of the plurality of electrical contacts in a manner that allows a combined vector electrical pulse train to be characterized by a pulse rate for at least a portion of the vector electrical pulse train that is equal to or greater than twice the frequency of the individual pulse trains, wherein at least one electrical pulse train has a frequency of between 2 kHz and 6 kHz.
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Specification