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Inorganic nanoparticle matrices for sample analysis

  • US 10,191,028 B1
  • Filed: 06/04/2004
  • Issued: 01/29/2019
  • Est. Priority Date: 06/06/2003
  • Status: Active Grant
First Claim
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1. A method of preparing and analyzing a tissue sample comprising the steps of:

  • combining the tissue sample with a matrix, said matrix comprising ionized inorganic nanoparticles wherein the combining step further comprises the step of injecting the matrix within a near surface layer of a slice of the tissue sample, wherein the near surface layer comprises a first few nanometers of the slice of the tissue sample, and,analyzing said combined tissue sample and matrix by laser desorption mass spectrometry.

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