Microarray electrodes useful with analyte sensors and methods for making and using them
First Claim
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1. A single sensor electrode comprising:
- a base layer;
a plurality of electrically conductive members disposed on the base layer in an array, wherein;
the array comprises at least 10 electrically conductive members that form the single sensor electrode;
the base comprises a plurality of indentations and the plurality of electrically conductive members are individually positioned within the plurality of indentations;
the at least 10 electrically conductive members each comprise an electroactive surface shaped as a circular disc and adapted to sense fluctuations in electrical current;
the array of electrically conductive members that form the single electrode is coupled to a common electrical conduit; and
the array of electrically conductive members is coupled to the common electrical conduit so as to be electrically linked as a group.
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Abstract
Embodiments of the invention provide analyte sensors having optimized electrodes and/or configurations of electrode elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.
126 Citations
15 Claims
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1. A single sensor electrode comprising:
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a base layer; a plurality of electrically conductive members disposed on the base layer in an array, wherein; the array comprises at least 10 electrically conductive members that form the single sensor electrode; the base comprises a plurality of indentations and the plurality of electrically conductive members are individually positioned within the plurality of indentations; the at least 10 electrically conductive members each comprise an electroactive surface shaped as a circular disc and adapted to sense fluctuations in electrical current; the array of electrically conductive members that form the single electrode is coupled to a common electrical conduit; and the array of electrically conductive members is coupled to the common electrical conduit so as to be electrically linked as a group. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An analyte sensor apparatus comprising:
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a base layer; a working electrode comprising a plurality of electrically conductive members disposed on the base layer in an array, wherein; the array comprises at least 10 electrically conductive members that form the working electrode; the base comprises a plurality of indentations and the plurality of electrically conductive members are individually positioned within the plurality of indentations; the at least 10 electrically conductive members each comprise an electroactive surface shaped as a circular disc and adapted to sense fluctuations in electrical current; the working electrode is coupled to a power source adapted to sense fluctuations in electrical current of the at least 10 electrically conductive members that form the working electrode; and the electrically conductive members that form the working electrode are coupled to the power source by a common electrical conduit so that they are electrically linked as a group; an analyte sensing layer disposed over the array of electrically conductive members that form the working electrode, wherein the analyte sensing layer detectably alters the electrical current at the working electrode in the presence of an analyte; and an analyte modulating layer disposed over the analyte sensing layer, wherein the analyte modulating layer modulates the diffusion of analyte therethrough. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15)
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Specification