Blood sampling transfer device and blood separation and testing system
First Claim
1. A blood sampling transfer device adapted to receive a blood sample having a cellular portion and a plasma portion, the blood sampling transfer device comprising:
- a first component comprising at least two electrically driven internal miniature pumps; and
a second component removably connected to the first component, the second component comprising;
an inlet port,a flow channel,an outlet port, the inlet port and the outlet port in fluid communication via the flow channel,a filter disposed within the flow channel between the inlet port and the outlet port,a first chamber defined between the inlet port and the filter, anda transfer chamber defined between the filter and the outlet port;
wherein the inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps, and wherein the filter traps the cellular portion and allows the plasma portion to pass through the filter and into the transfer chamber; and
wherein the at least two electrically driven internal miniature pumps are connected to one another via the first chamber to oscillate the blood sample back and forth over the filter, in which one electrically driven internal miniature pump is connected to a first side of the first chamber and another electrically driven internal miniature pump is connected to a second opposing side of the first chamber such that the filter is disposed between the one electrically driven internal miniature pump and the another electrically driven internal miniature pump.
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Accused Products
Abstract
A blood sampling transfer device that is adapted to receive a blood sample having a cellular portion and a plasma portion is disclosed. The blood sampling transfer device is able to separate the plasma portion from the cellular portion. After separation, the blood sampling transfer device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The blood sampling transfer device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The blood sampling transfer device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the blood sampling transfer device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results.
56 Citations
21 Claims
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1. A blood sampling transfer device adapted to receive a blood sample having a cellular portion and a plasma portion, the blood sampling transfer device comprising:
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a first component comprising at least two electrically driven internal miniature pumps; and a second component removably connected to the first component, the second component comprising; an inlet port, a flow channel, an outlet port, the inlet port and the outlet port in fluid communication via the flow channel, a filter disposed within the flow channel between the inlet port and the outlet port, a first chamber defined between the inlet port and the filter, and a transfer chamber defined between the filter and the outlet port; wherein the inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps, and wherein the filter traps the cellular portion and allows the plasma portion to pass through the filter and into the transfer chamber; and wherein the at least two electrically driven internal miniature pumps are connected to one another via the first chamber to oscillate the blood sample back and forth over the filter, in which one electrically driven internal miniature pump is connected to a first side of the first chamber and another electrically driven internal miniature pump is connected to a second opposing side of the first chamber such that the filter is disposed between the one electrically driven internal miniature pump and the another electrically driven internal miniature pump. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A blood separation and testing system for a blood sample having a cellular portion and a plasma portion, the blood separation and testing system comprising:
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a blood sampling transfer device adapted to receive the blood sample, the blood sampling transfer device comprising; a first component comprising at least two electrically driven internal miniature pumps, and a second component removably connected to the first component, the second component comprising; an inlet port, a flow channel, an outlet port, the inlet port and the outlet port in fluid communication via the flow channel, a filter disposed within the flow channel between the inlet port and the outlet port, a first chamber defined between the inlet port and the filter, and a transfer chamber defined between the filter and the outlet port, wherein the inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps, and wherein the filter traps the cellular portion and allows the plasma portion to pass through the filter and into the transfer chamber, and wherein the at least two electrically driven internal miniature pumps are connected to one another via the first chamber to oscillate the blood sample back and forth over the filter, in which one electrically driven internal miniature pump is connected to a first side of the first chamber and another electrically driven internal miniature pump is connected to a second opposing side of the first chamber such that the filter is disposed between the one electrically driven internal miniature pump and the another electrically driven internal miniature pump; and a blood testing device having a receiving port connectable to the outlet port of the blood sampling transfer device for closed transfer of a portion of the plasma portion from the transfer chamber to the blood testing device. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. A blood sampling transfer system adapted to receive a blood sample, the blood sampling transfer system comprising:
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a reusable component comprising at least two electrically driven internal miniature pumps; a first disposable component removably connectable to the reusable component, the first disposable component having a first inlet port, wherein the first inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps; and a second disposable component removably connectable to the reusable component, the second disposable component having a second inlet port, wherein the second inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps, wherein the first disposable component and the second disposable component are separated from one another and are used separately with the reusable component, and wherein the at least two internal miniature pumps are connected to the first disposable component and the second disposable component, wherein the at least two internal miniature pumps are connected to one another so as to oscillate the blood sample back and forth within, respectively, the first disposable component and the second disposable component, in which one electrically driven internal miniature pump is connected to a first side of a first chamber in the first disposable component or second disposable component and another electrically driven internal miniature pump is connected to a second opposing side of the first chamber in the first disposable component or the second disposable component with a filter disposed between the one electrically driven internal miniature pump and the another electrically driven internal miniature pump.
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21. A blood sampling transfer system adapted to receive a blood sample having a cellular portion and a plasma portion, the blood sampling transfer system comprising:
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a reusable component comprising at least two electrically driven internal miniature pumps; a first disposable component removably connectable to the reusable component, the first disposable component having a first inlet port, a first flow channel, a first outlet port, the first inlet port and the first outlet port in fluid communication via the first flow channel, a first filter disposed within the first flow channel between the first inlet port and the first outlet port, a first chamber between the first inlet port and the first filter, and a first transfer chamber between the first filter and the first outlet port, wherein the first inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps, wherein the first filter traps the cellular portion and allows the plasma portion to pass through the first filter and into the first transfer chamber, and wherein the at least two electrically driven internal miniature pumps are connected to one another via the first chamber to oscillate the blood sample back and forth over the first filter, in which one electrically driven internal miniature pump is connected to a first side of the first chamber and another electrically driven internal miniature pump is connected to a second opposing side of the first chamber such that the first filter is disposed between the one electrically driven internal miniature pump and the another electrically driven internal miniature pump; and a second disposable component removably connectable to the reusable component, the second disposable component having a second inlet port, a second flow channel, a second outlet port, the second inlet port and the second outlet port in fluid communication via the second flow channel, a second filter disposed within the second flow channel between the second inlet port and the second outlet port, a second chamber between the second inlet port and the second filter, and a second transfer chamber between the second filter and the second outlet port, wherein the second inlet port receives the blood sample upon actuation of the at least two electrically driven internal miniature pumps, wherein the second filter traps the cellular portion and allows the plasma portion to pass through the second filter and into the second transfer chamber, and wherein the at least two electrically driven internal miniature pumps are connected to one another via the second chamber to oscillate the blood sample back and forth over the second filter, in which one electrically driven internal miniature pump is connected to a first side of the second chamber and another electrically driven internal miniature pump is connected to a second opposing side of the second chamber such that the second filter is disposed between the one electrically driven internal miniature pump and the another electrically driven internal miniature pump, wherein the first disposable component and the second disposable component are separated from one another and are used separately with the reusable component.
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Specification