Transcatheter valve prosthesis

• US 10,195,027 B2
• Filed: 11/04/2016
• Issued: 02/05/2019
• Est. Priority Date: 11/04/2016
• Status: Active Grant

• Current Assignee: HighLife SAS
• Original Assignee: HighLife SAS
• Inventors: Nasr, Malek
• Primary Examiner(s): Sharma, Yashita
• Application Number:
  US15/343,792
• Publication Number:
  US 20180125650A1
• Time in Patent Office: 823 Days
• Field of Search: 623 11- 238
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2415 Manufacturing methods
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses
• CPC Class Codes: A61F 2002/828 Means for connecting a plurality of stents allowing flexibility of the whole structure
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/001 Figure-8-shaped, e.g. hourglass-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2250/0029 differing in bending or flexure capacity
• CPC Class Codes: A61F 2250/0036 differing in thickness
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability

Abstract

A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end such that the outflow end includes a proximal section and a plurality of beams. The plurality of beams being disposed distally of the proximal section in an outflow direction. Additionally, the tubular body including struts with peaks and valleys at the inflow end of the tubular body such that the proximal section of the outflow end is disposed distally of the peaks and valleys in the outflow direction. Furthermore, the tubular body being configured such that movement of the proximal section of the outflow end radially inward causes the inflow end to flare radially outward, and an arrangement of the struts being configured such that movement of the peaks radially inward causes the valleys to flare radially outward.

Claims

1. A heart valve system, the system comprising:

a radially self-expandable tubular body having an inflow end and an outflow end,

the outflow end including a proximal section and a plurality of beams, the plurality of beams being disposed distally of the proximal section in an outflow direction, and

the tubular body including struts with peaks and valleys at the inflow end of the tubular body such that the proximal section of the outflow end is disposed distally of the peaks and valleys in the outflow direction; and

a valve coupled to the tubular body, the valve including a plurality of valve leaflets,

wherein (i) movement of the proximal section of the outflow end of the tubular body radially inward causes the inflow end of the tubular body to flare radially outward, and/or (ii) movement of the peaks of the tubular body radially inward causes the valleys of the tubular body to flare radially outward.

2. The system according to claim 1, wherein the valleys are located closer to the outflow end of the tubular body than the peaks.

3. The system according to claim 1, further including a fabric disposed on an outer surface of the tubular body such that movement of the valleys radially outward causes the fabric to flare radially outward.

4. The system according to claim 1, wherein the tubular body includes struts with different thicknesses.

5. The system according to claim 4, wherein the struts with different thicknesses form first cells and second cells, the first cells have struts with relatively smaller thicknesses and the second cells have struts with relatively larger thicknesses so that the first cells and the second cells expand and open uniformly.

6. The system according to claim 5, further including a third cell that includes a strut with the relatively smaller thickness and a strut with the relatively larger thickness.

7. The system according to claim 1, further including a trapping member configured to form at least a partial loop encircling the tubular body to trap portions of native valve leaflets and/or chords.

8. The system according to claim 1, wherein the inflow end of the tubular body includes struts with an S-shape.

9. The system according to claim 8, wherein the struts with the S-shape are directly connected to the peaks.

10. The system according to claim 9, wherein the peaks and valleys are both disposed above the struts with the S-shape in an inflow direction.

11. The system according to claim 1, wherein the tubular body has a proximal-most end at the inflow end and a distal-most end at the outflow end, the peaks and valleys forming the proximal-most end.

12. The system according to claim 11, wherein the plurality of beams forms the distal-most end.

13. The system according to claim 1, wherein connection points link the inflow end of the tubular body and the plurality of beams, a number of connection points being equivalent to a number of the valve leaflets.

14. The system according to claim 1, wherein the valve leaflets extend distally of the outflow end of the tubular body in the outflow direction.

15. The system according to claim 1, wherein the valve leaflets extend entirely distally of the proximal section of the outflow end in the outflow direction.