Pen-type injector

• US 10,195,353 B2
• Filed: 06/30/2014
• Issued: 02/05/2019
• Est. Priority Date: 03/03/2003
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Veasey, Robert Frederick, Langley, Christopher Nigel, Wimpenny, Steven
• Primary Examiner(s): Patel, Shefali
• Application Number:
  US14/319,365
• Publication Number:
  US 20140316343A1
• Time in Patent Office: 1,681 Days
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2422 using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
• CPC Class Codes: A61M 5/31501 Means for blocking or restricting the movement of the rod or piston A61M5/5013 takes precedence
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31526 by means of stepwise axial movements, e.g. ratchet mechanisms or detents
• CPC Class Codes: A61M 5/31528 by means of rotational movements, e.g. screw-thread mechanisms
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/3155 by rotational movement of dose setting member, e.g. during setting or filling of a syringe
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/3156 using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
• CPC Class Codes: A61M 5/31583 based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

A pen-type injector is improved so that a user may select a delivery dose of a medicinal product from a multidose cartridge. The injector includes a housing, a cartridge containing the medicinal product retained within the housing, a piston rod, a dose selecting member to select the dose of medicinal product to be expelled, and a drive member to expel the selected dose of the medicinal product. The housing is formed unitary so that the dose selecting member and the drive member are moveably retained within the housing. The injector may include a ratchet associated with an insert to ensure the piston rod only rotates in a single direction through the insert, a button located on the drive member, and a clutch which upon depression of the button prevents rotation between the dose selecting member and the drive member.

Claims

1. A drive mechanism for use in a drug delivery device comprising:

a housing;

a dose dial sleeve located in the housing and having a helical track configured to allow the dose dial sleeve to rotate and translate relative to the housing during dose setting and dose delivery;

a drive sleeve releasably connected to the dose dial sleeve and comprising a central receiving area;

a piston rod extending through a threaded circular opening in the housing, where the piston rod has a first end and a second end, where the first end comprises a thread, the second end having a larger diameter than the first end and comprises a U-shaped cross-section having limbs extending longitudinally in a proximal direction, where the limbs are received within the drive sleeve; and

a button of a generally T-shaped configuration comprising a stem provided with a peripheral bead,

wherein the stem of the button is retained within the central receiving area with the peripheral bead being retained in a peripheral recess of the drive sleeve,

wherein the button is able to freely rotate with respect to the drive sleeve.

2. The drive mechanism of claim 1 where a pressure foot is attached to the first end of the piston rod on a first side of a web.

3. The drive mechanism of claim 2 where the pressure foot is reversible.

4. The drive mechanism of claim 1 where a clicker is provided between the dose dial sleeve and the drive sleeve.

5. The drive mechanism of claim 1 where the piston rod has a dual start thread.

6. The drive mechanism of claim 1 further comprising a clutch comprising a plurality of radially extending longitudinally directed teeth, where a radial separation of the teeth corresponds to a unit dose of a medicinal product, where the clutch is configured to releasably and rotationally fix together the dose dial sleeve and the drive sleeve.

7. The drive mechanism of claim 1, wherein the first end extends through a circular opening in a web that is located in the housing.

8. The drive mechanism of claim 1 where the second end of the piston rod is configured to engage an internal surface of the drive sleeve.