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Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups

  • US 10,202,602 B2
  • Filed: 08/25/2016
  • Issued: 02/12/2019
  • Est. Priority Date: 05/28/2010
  • Status: Active Grant
First Claim
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1. An oligomer comprising a backbone, the backbone comprising a sequence of morpholino ring structures joined by intersubunit linkages of type (A), (B), or combinations thereof, wherein each morpholino ring structure supports a base-pairing moiety, such that the oligomer compound can bind in a sequence-specific manner to a target nucleic acid, and wherein the oligomer comprises a 3′

  • terminus, a 5′

    terminus and has the following structure (XVII);

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