Fluorescent substance detection system

• US 10,203,283 B2
• Filed: 11/06/2017
• Issued: 02/12/2019
• Est. Priority Date: 07/17/2014
• Status: Active Grant

• Current Assignee: Koç University, Kuantag Nanoteknolojiler Gelistirme Ve Uretim A.S.
• Original Assignee: Koç University, Kuantag Nanoteknolojiler Gelistirme Ve Uretim A.S.
• Inventors: Urey, Hakan, Akgun, Osman Vedat, Heves, Emre, Civitci, Fehmi, Can, Basarbatu
• Primary Examiner(s): Porta, David P
• Assistant Examiner(s): Boosalis, Fani P
• Application Number:
  US15/805,123
• Publication Number:
  US 20180100800A1
• Time in Patent Office: 463 Days
• CPC Class Codes: G01N 2021/6421 Measuring at two or more wavelengths
• CPC Class Codes: G01N 2021/6484 Optical fibres
• CPC Class Codes: G01N 21/643 non-biological material
• CPC Class Codes: G01N 21/645 Specially adapted constructive features of fluorimeters
• CPC Class Codes: G01N 21/8507 Probe photometers, i.e. with optical measuring part dipped into fluid sample
• CPC Class Codes: G01N 2201/0624 Compensating variation in output of LED source
• CPC Class Codes: G01N 2201/0826 Fibre array at source, distributing
• CPC Class Codes: G01N 2201/0833 Fibre array at detector, resolving

Abstract

In the present invention, a fluorescent substance detection system (S) for detecting fluorescent substances in any environment is provided. Said detection system (S) comprises at least one illumination unit (1) which emits light to said environment in order to excite said substances; detection units (2), at least at a number equal to the number of types of fluorescent substances, for detecting emissions coming from said excited fluorescent substances and bandpass filters (3), each connected to detection units (2) one by one, wherein bandpass filters (3) have a center wavelength matched to the center emission wavelength of corresponding fluorescent substance.

Claims

1. A detection system for detecting fluorescent materials mixed in an environment in order to identify the environment, the fluorescent materials having known discrete emission spectrums for coding information to identify the environment that the fluorescent materials are mixed in, wherein the environment is highly absorbent and highly fluorescent, and wherein the environment includes one of liquid medium, gas medium and solid medium, the system comprising:

at least one illumination unit emitting light to the environment in order to excite the fluorescent materials to generate discrete emission spectrums used for generating coding information to identify the environment, the light emitted from the at least one illumination unit also generating fluorescence emissions in the environment along with the discrete emission spectrums from the fluorescent materials;

at least one detection unit for detecting discrete emission spectrums emitted from the fluorescent materials in response to light emitted from the illumination unit;

at least one signal processing unit connected to the at least one detection unit to receive signals including the discrete emission spectrums of the fluorescent materials from the at least one detection unit and process the signals to decode the coding information in order to identify the environment; and

at least one background detector for detecting the fluorescent emissions of the environment, the at least one background detector being in connection with the at least one signal processing unit to apply dynamic background subtraction method to extract the fluorescent emissions only from the fluorescent materials and employ them to identify the environment.

2. The system of claim 1, wherein the at least one detection unit includes detection units that are at least at a number equal to the number of types of the fluorescent materials.

3. The system of claim 1 further including bandpass filters paired with the at least one detection unit, wherein the bandpass filter of each detection unit matches a center emission wavelength of the discrete emission spectrum of one of the fluorescent materials.

4. The system of claim 3 further including at least one excitation transmitter which transmits light emitted from the at least one illumination unit to the environment.

5. The system of claim 4 further including at least one collection transmitter which transmits emissions of the fluorescent materials to the detection unit.

6. The system of claim 5, wherein the at least one excitation transmitter and the at least one collection transmitter are in the form of light carriers.

7. The system of claim 6, wherein the at least one excitation transmitter and the at least one collection transmitter are in the form of fiber.

8. The system of claim 5, wherein the bandpass filters are coupled with the at least one collection transmitter.

9. The system of claim 5, further comprising a transmitting probe, wherein the at least one excitation transmitter, the at least one collection transmitter and the bandpass filters are placed in the transmitting probe.

10. The system of claim 9, wherein the transmitting probe comprises a compound parabolic concentrator.

11. The system of claim 1, wherein the at least one illumination unit comprises at least one light source for exciting the fluorescent materials.

12. The system of claim 1, wherein the at least one illumination unit further comprises at least one driver circuit for controlling the at least one light source.

13. The system of claim 12, wherein the at least one illumination unit further comprises a photodiode to monitor the output power of the at least one light source.

14. The system of claim 1, wherein the detection units comprise a photodetector read out circuitry.

15. The system of claim 14, wherein the detection units comprise at least one integration capacitor, which filters small fluctuations on the signal coming from the photodetector read out circuitry.

16. The system of claim 1 further comprising a single transmitter which is both used for transmitting light emitted from the at least one illumination unit to reach the environment and transmitting emissions of the fluorescent materials to reach the detection units.

17. The system of claim 16 further comprising dichroic mirrors for separating light from the at least one illumination unit and different wavelength fluorescent materials.

18. The system of claim 1, wherein the fluorescent materials are at least one of one or more quantum dots and one or more light emitting molecules.

19. The system of claim 1, wherein the light emitted from the at least one illumination unit reaches to the environment by passing through the free space.

20. The system of claim 1, wherein emissions from the fluorescent materials reach to the detection unit by passing through the free space.