Strobilurin formulations

• US 10,206,391 B2
• Filed: 08/23/2012
• Issued: 02/19/2019
• Est. Priority Date: 12/22/2011
• Status: Active Grant

• Current Assignee: Vive Crop Protection Inc.
• Original Assignee: Vive Crop Protection Inc.
• Inventors: Li, Fugang, Pham, Hung Hoang, Gong, Rachel, Galas, Henry
• Primary Examiner(s): Pak, John
• Assistant Examiner(s): Schlientz, Nathan W
• Application Number:
  US14/367,473
• Publication Number:
  US 20140364310A1
• Time in Patent Office: 2,371 Days
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16
• CPC Class Codes: A01N 25/10 Macromolecular compounds
• CPC Class Codes: A01N 25/14 wettable
• CPC Class Codes: A01N 37/10 Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
• CPC Class Codes: A01N 37/50 the nitrogen atom being doubly bound to the carbon skeleton
• CPC Class Codes: A01N 43/40 six-membered rings
• CPC Class Codes: A01N 43/54 1,3-Diazines; Hydrogenated 1,3-diazines
• CPC Class Codes: A01N 43/56 1,2-Diazoles; Hydrogenated 1,2-diazoles
• CPC Class Codes: A01N 43/76 1,3-Oxazoles; Hydrogenated 1,3-oxazoles
• CPC Class Codes: A01N 43/88 six-membered rings with three ring hetero atoms
• CPC Class Codes: A01N 47/24 containing the groups , or; Thio analogues thereof
• CPC Class Codes: A01N 57/20 containing acyclic or cycloaliphatic radicals
• CPC Class Codes: C05G 3/60 Biocides or preservatives, e.g. disinfectants, pesticides or herbicides; Pest repellants or attractants

Abstract

The present disclosure describes a formulation including a nanoparticle including a polymer-associated strobilurin compound with an average diameter of between about 1 nm and about 500 nm; wherein the polymer is a polyelectrolyte, and a dispersant or a wetting agent. The disclosure describes various formulations and formulating agents that can be included in the formulations. Additionally, the disclosures describes application to various plants and fungi as well as advantages of the disclosed formulations.

Claims

1. A liquid formulation comprising:

nanoparticles comprising a polymer and a strobilurin compound with an average diameter of between about 1 nm and about 500 nm;

wherein the polymer is a polyelectrolyte copolymer comprised of between about 50 weight percent and about 95 weight percent methacrylic acid monomers and between about 50 weight percent and about 5 weight percent ethyl acrylate or styrene monomers and the strobilurin compound is associated with the polymer;

between about 0.5 weight percent and about 5 weight percent of a naphthalene sulfonate condensate dispersant;

between about 0.5 weight percent and about 5 weight percent of a sodium dodecylbenzene sulfonate wetting agent;

between about 0.1 weight percent and about 1 weight percent of an anti-foaming agent;

between about 0.01 weight percent and about 0.1 weight percent a preservative; and

water;

wherein the nanoparticles comprise between about 1 weight percent and about 50 weight percent of the formulation.

2. The liquid formulation of claim 1, wherein the strobilurin compound comprises between about 5 weight percent and about 30 weight percent of the formulation.

3. The liquid formulation of claim 1, wherein a ratio of a weight percent of the strobilurin compound to a weight percent of the polymer is between about 1:

1 to 6;

1.

4. The liquid formulation of claim 1, wherein the nanoparticles have a melting point of less than 80°

C.

5. The liquid formulation of claim 1, wherein the strobilurin compound is selected from the group consisting of azoxystrobin, picoxystrobin, pyraclostrobin, orysastrobin, metominostrobin, fluoxastrobin and trifloxystrobin.

6. The liquid formulation of claim 1, further comprising a thickener.

7. The liquid formulation of claim 6, wherein the thickener comprises between about 0.05 weight percent and about 5 weight percent of the formulation.

8. The liquid formulation of claim 1, further comprising an anti-freeze agent.

9. The liquid formulation of claim 8, wherein the anti-freeze agent comprises between about 1 weight percent and about 10 weight percent of the formulation.

10. The liquid formulation of claim 1, further comprising an additional pesticidal compound.

11. The liquid formulation of claim 10, wherein the additional pesticidal compound is a fungicide.

12. The liquid formulation of claim 10, wherein the additional pesticide comprises between about 5 weight percent and about 30 weight percent of the formulation.

13. The liquid formulation of claim 1, where the polymer is a poly(methacrylic acid-co-ethyl acrylate) polymer.

14. The liquid formulation of claim 1, further comprising a liquid fertilizer.

15. The liquid formulation of claim 14, wherein the fertilizer comprises at least one of the elements selected from the group consisting of boron, copper, manganese, iron, chorine, molybdenum, zinc sulfur, nitrogen, phosphorus and potassium.

16. The liquid formulation of claim 1, wherein the polymer is cross-linked.

17. A method of controlling fungi comprising applying the liquid formulation of claim 1 to a plant, a location near a plant, or to soil where a seed is or will be planted.

18. The method of claim 17, wherein the liquid formulation is applied to a corn plant at a concentration of between about 11 and about 109 grams of the strobilurin compound per hectare, and the fungi are selected from the group consisting of Rust (Puccinia sorghi), anthracnose leaf blight (Colletotrichum graminicola), Gray leaf spot (Cercospora sorghi), Northern corn leaf blight (Setosphaeria turcica), Northern corn leaf spot (Cochliobolus carbonum), Southern corn leaf blight (Cochliobolus heterostrophus) and Eye spot (Aureobasidium zeae).

19. The method of claim 17, wherein the liquid formulation is applied to a soybean plant at a concentration of between about 11 and about 109 grams of the strobilurin compound per hectare, and the fungi are selected from the group consisting of Aerial blight (Rhizoctonia solani), Anthracnose (Colletotrichum truncatum), Alternaria leaf spot (Alternaria spp.), Brown spot (Septoria glycines) Cercospora blight and leaf spot (Cercospora kikuchii), Frogeye leaf spot (Cercospora sojina), Pod and stem blight (Diaporthe phaseolorum), and the strobilurin compound is azoxystrobin.