Method and system for providing integrated analyte monitoring and infusion system therapy management

• US 10,206,629 B2
• Filed: 04/28/2014
• Issued: 02/19/2019
• Est. Priority Date: 08/07/2006
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Jennewine, R. Curtis
• Primary Examiner(s): Natnithithadha, Navin
• Application Number:
  US14/263,996
• Publication Number:
  US 20140235985A1
• Time in Patent Office: 1,758 Days
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

Method and system for providing diabetes management and insulin therapy based on substantially real time glucose monitoring system is provided.

Claims

1. A method using one or more processors, comprising:

extrapolating a projected glucose level using only rate of change of a monitored glucose level;

updating an insulin sensitivity factor on an ongoing basis based at least in part on a comparison of the projected glucose level with the monitored glucose level;

generating a modification to a therapy profile associated with insulin administration based on the updated insulin sensitivity factor and the monitored glucose level; and

initiating the insulin administration based on the modified therapy profile using an infusion device.

2. The method of claim 1, further including displaying the generated modification to the therapy profile.

3. The method of claim 2, wherein the generated modification to the therapy profile is displayed as one or more of an alphanumeric output display, a graphical output display, an icon display, a video output display, a color display or an illumination display.

4. The method of claim 1, further including determining, after initiating the insulin administration, whether the insulin administration is having an intended therapeutic effect.

5. The method of claim 1, wherein the therapy profile further includes one or more of a basal profile, a correction bolus, or a temporary basal profile.

6. The method of claim 1, wherein generating the modification to the therapy profile associated with the monitored glucose level includes retrieving a current glucose rate of change information.

7. The method of claim 6, wherein generating the modification to the therapy profile includes determining a modified glucose rate of change information based on the data associated with the monitored glucose level.

8. The method of claim 7, further including determining a glucose level projection information based on the modified glucose rate of change information.

9. The method of claim 1, wherein the infusion device is one of an external insulin pump, an implantable insulin pump, an on-body patch pump, a pen-type injection device, an inhalable insulin delivery system, or a transdermal insulin delivery system.

10. An apparatus, comprising:

an interface unit;

one or more processors coupled to the interface unit; and

a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to extrapolate a projected glucose level using only rate of change of monitored glucose level, to update an insulin sensitivity factor on an ongoing basis based at least in part on a comparison of the projected glucose level with the monitored glucose level, to generate a modification to a therapy profile associated with insulin administration based on the updated insulin sensitivity factor and the monitored glucose level, and to initiate the insulin administration based on the modified therapy profile using an infusion device.

11. The apparatus of claim 10, wherein the interface unit includes an input unit and an output unit, the input unit configured to receive the data associated with the monitored glucose level, and the output unit configured to output the generated modification to the therapy profile.

12. The apparatus of claim 10, wherein the interface unit and the one or more processors are operatively coupled to one or more of a housing of the infusion device or a housing of an analyte monitoring system component.

13. The apparatus of claim 10, wherein the memory is further configured for storing instructions which, when executed by the one or more processors, causes the one or more processors to display the generated modification to the therapy profile.

14. The apparatus of claim 13, wherein when the memory is configured for storing instructions which, when executed by the one or more processors, causes the one or more processors to display the generated modification to the therapy profile as one or more of an alphanumeric output display, a graphical output display, an icon display, a video output display, a color display or an illumination display.

15. The apparatus of claim 10, wherein the therapy profile further includes one or more of a basal profile, a correction bolus, or a temporary basal profile.

16. The apparatus of claim 10, wherein the memory is further configured for storing instructions which, when executed by the one or more processors, causes the one or more processors to retrieve a current glucose rate of change information.

17. The apparatus of claim 16, wherein the memory is further configured for storing instructions which, when executed by the one or more processors, causes the one or more processors to determine a modified glucose rate of change information based on the data associated with the monitored glucose level.

18. The apparatus of claim 17, wherein the memory is further configured for storing instructions which, when executed by the one or more processors, causes the one or more processors to determine a glucose level projection information based on the modified glucose rate of change information.

19. The apparatus of claim 10, wherein the memory is further configured for storing instructions which, when executed by the one or more processors, causes the one or more processors to determine, after initiating the insulin administration, whether the insulin administration is having an intended therapeutic effect.

20. The apparatus of claim 10, wherein the infusion device is one of an external insulin pump, an implantable insulin pump, an on-body patch pump, a pen-type injection device, an inhalable insulin delivery system, or a transdermal insulin delivery system.