Pacing mode switching in a ventricular pacemaker

• US 10,207,116 B2
• Filed: 12/01/2016
• Issued: 02/19/2019
• Est. Priority Date: 12/01/2016
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sheldon, Todd J, Cho, Yong K, Demmer, Wade M, Erickson, Mark K, Splett, Vincent E
• Primary Examiner(s): Levicky, William J
• Application Number:
  US15/366,993
• Publication Number:
  US 20180154154A1
• Time in Patent Office: 810 Days
• CPC Class Codes: A61N 1/36535 controlled by body position or posture
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/36578 controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone
• CPC Class Codes: A61N 1/3688 configured for switching the pacing mode, e.g. from AAI to DDD
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

An intracardiac ventricular pacemaker is configured to operate in in a selected one of an atrial-tracking ventricular pacing mode and a non-atrial tracking ventricular pacing mode. A control circuit of the pacemaker determines at least one motion signal metric from the motion signal, compares the at least one motion signal metric to pacing mode switching criteria; and responsive to the pacing mode switching criteria being satisfied, switches from the selected one of the non-atrial tracking pacing mode and the atrial tracking pacing mode to the other one of the non-atrial tracking pacing mode and the atrial tracking pacing mode for controlling ventricular pacing pulses delivered by the pacemaker.

Claims

1. An intracardiac ventricular pacemaker, comprising:

a pulse generator configured to generate and deliver pacing pulses to a ventricle of a patient'"'"'s heart via electrodes coupled to the pacemaker;

a motion sensor configured to produce a motion signal; and

a control circuit configured to receive the motion signal and communicate with the pulse generator, the control circuit configured to;

detect atrial systolic events from the motion signal;

operate in a selected one of an atrial-tracking ventricular pacing mode and a non-atrial tracking ventricular pacing mode;

while operating in the selected one of the atrial-tracking ventricular pacing mode and the non-atrial tracking ventricular pacing mode, determine at least one motion signal metric based on a rate of at least some of the detected atrial systolic events;

determine a patient physical activity metric from the motion signal;

set a pacing mode switching threshold based on the patient physical activity metric;

compare the at least one motion signal metric to the pacing mode switching threshold; and

responsive to the pacing mode switching threshold being satisfied, switch from the selected one of the non-atrial tracking pacing mode and the atrial tracking pacing mode to the other one of the non-atrial tracking pacing mode and the atrial tracking pacing mode for controlling the pacing pulses delivered by the pulse generator.

2. The pacemaker of claim 1, wherein the the at least one motion signal metric is further based on the patient physical activity metric determined from from the motion signal.

3. The pacemaker of claim 1, wherein the rate of the at least some of the detected atrial systolic events comprises

a count of the at least some of the detected atrial systolic events.

4. The pacemaker of claim 1, wherein the control circuit is configured to:

determine a patient posture from the motion signal; and

wherein the at least one motion signal metric is further based on the patient posture.

5. The pacemaker of claim 1, wherein the control circuit is configured to determine the at least one motion signal metric by processing the motion signal over a predetermined time segment.

6. The pacemaker of claim 1, wherein the control circuit is configured to:

extend a ventricular pacing rate interval for at least one ventricular cycle;

detect an atrial systolic event from the motion signal during the extended ventricular pacing rate interval; and

determine if the pacing mode switching threshold are met in response to detecting the atrial systolic event.

7. The pacemaker of claim 6, wherein:

the pacemaker further includes a sensing circuit for receiving a cardiac electrical signal via electrodes coupled to the pacemaker;

the control circuit is further configured to;

detect at least one of;

a premature ventricular contraction from the cardiac electrical signal,

a decreased patient physical activity from the motion signal, and

a change in patient body posture from the motion signal; and

extend the ventricular pacing rate interval in response to detecting at least one of the premature ventricular contraction, the decreased patient physical activity, and the change in patient posture.

8. The pacemaker of claim 6, wherein the control circuit is further configured to:

periodically extend the ventricular pacing rate interval at a frequency that is dependent on the patient physical activity metric.

9. The pacemaker of claim 1, wherein the control circuit is further configured to:

determine a patient condition from the motion signal; and

set the pacing mode switching threshold based on the patient condition.

10. The pacemaker of claim 1, wherein the control circuit is configured to:

determine a first motion signal metric from the motion signal;

compare the first motion signal metric to a first pacing mode switching criterion;

determine a second motion signal metric from the motion signal;

compare the second motion signal metric to a second pacing mode switching criterion; and

switching the pacing mode in response to the first and the second pacing mode switching criterion being satisfied.

11. The pacemaker of claim 1, wherein the control circuit is further configured to:

detect a plurality of the atrial systolic events from the motion signal; and

determine the at least one motion signal metric by determining a stability of the plurality of atrial systolic events.

12. The pacemaker of claim 1, where in the control module is further configured to:

switch from the atrial tracking pacing mode to a first non-atrial tracking pacing mode for a temporary interval; and

switch from the first non-atrial tracking pacing mode to a second non-atrial tracking pacing mode in response to the temporary interval expiring.

13. The pacemaker of claim 1, further comprising:

a housing enclosing the pulse generator, the motion sensor, and the control circuit; and

at least one electrode carried by the housing and coupled to the pulse generator for delivering the ventricular pacing pulses.

14. The pacemaker of claim 1, wherein the control circuit is configured to:

switch from the atrial-tracking ventricular pacing mode to the non-atrial tracking pacing mode in response to the rate of the detected atrial systolic events being less than the pacing mode switching threshold.

15. An intracardiac ventricular pacemaker comprising:

a pulse generator configured to generate and deliver pacing pulses to a ventricle of a patient'"'"'s heart via electrodes coupled to the pacemaker;

a motion sensor configured to produce a motion signal; and

a control circuit configured to receive the motion signal and communicate with the pulse generator, the control circuit configured to;

detect an atrial systolic event from the motion signal;

detect a ventricular diastolic event from the motion signal;

operate in a selected one of an atrial-tracking ventricular pacing mode and a non-atrial tracking ventricular pacing mode;

while operating in the selected one of the atrial-tracking ventricular pacing mode and the non-atrial tracking ventricular pacing mode, determine at least one motion signal metric based on a time interval from the ventricular diastolic event to the atrial systolic event;

compare the at least one motion signal metric to pacing mode switching criteria; and

responsive to the pacing mode switching criteria being satisfied, switch from the selected one of the non-atrial tracking pacing mode and the atrial tracking pacing mode to the other one of the non-atrial tracking pacing mode and the atrial tracking pacing mode for controlling the pacing pulses delivered by the pulse generator.

16. A method performed by an intracardiac ventricular pacemaker having a motion sensor configured to produce a motion signal, the method comprising:

detecting atrial systolic events from the motion signal;

operating in a selected one of an atrial-tracking ventricular pacing mode and a non-atrial tracking ventricular pacing mode;

while operating in the selected one of the atrial-tracking ventricular pacing mode and the non-atrial tracking ventricular pacing mode, determining by a control circuit of the pacemaker at least one motion signal metric based on a rate of at least some of the detected atrial systolic events;

determining a patient physical activity metric from the motion signal;

setting a pacing mode switching threshold based on the patient physical activity metric;

comparing the at least one motion signal metric to pacing mode switching criteria,

wherein the comparing comprises comparing the rate of the at least some of the detected atrial systolic events to the pacing mode switching threshold; and

responsive to the pacing mode switching criteria being satisfied, switching from the selected one of the non-atrial tracking pacing mode and the atrial tracking pacing mode to the other one of the non-atrial tracking pacing mode and the atrial tracking pacing mode for controlling ventricular pacing pulses delivered by the pacemaker.

17. The method of claim 16, wherein the at least one motion signal metric is further based on the patient physical activity metric.

18. The method of claim 16, wherein the rate of the at least some of the detected atrial systolic events comprises

a count of the at least some of the detected atrial systolic events.

19. The method of claim 16, further comprising determining a patient posture from the motion signal, and wherein the at least one motion signal metric is further based on the patient posture.

20. The method of claim 16, wherein determining the at least one motion signal metric comprises processing the motion signal over a predetermined time segment.

21. The method of claim 16, further comprising:

extending a ventricular pacing rate interval for at least one ventricular cycle;

detecting an atrial systolic event from the motion signal during the extended ventricular pacing rate interval; and

determining if the pacing mode switching criteria are met in response to detecting the atrial systolic event.

22. The method of claim 21, further comprising:

detecting by the control circuit at least one of;

a premature ventricular contraction from a cardiac electrical signal received by a sensing circuit of the pacemaker,

a decreased patient physical activity from the motion signal, and

a change in patient body posture from the motion signal; and

extending the ventricular pacing rate interval in response to detecting at least one of the premature ventricular contraction, the decreased patient physical activity, and the change in patient posture.

23. The method of claim 21, further comprising:

periodically extending the ventricular pacing rate interval at a frequency that is dependent on the patient physical activity metric.

24. The method of claim 16, further comprising:

determining a patient condition from the motion signal; and

setting, by the control circuit, the pacing mode switching criteria based on the patient condition.

25. The method of claim 16, further comprising:

determining a first motion signal metric from the motion signal;

comparing the first motion signal metric to a first pacing mode switching criterion;

determining a second motion signal metric from the motion signal;

comparing the second motion signal metric to a second pacing mode switching criterion; and

switching the pacing mode in response to the first pacing mode switching criterion and the second pacing mode switching criterion being satisfied.

26. The method of claim 16, further comprising:

detecting a plurality of the atrial systolic events from the motion signal; and

determining the at least one motion signal metric by determining a stability of the plurality of atrial systolic events.

27. The method of claim 16, wherein in switching from the atrial tracking pacing mode to the non-atrial tracking pacing mode comprises:

switching from the atrial tracking pacing mode to a first non-atrial tracking pacing mode for a temporary interval; and

switching from the first non-atrial tracking pacing mode to a second non-atrial tracking pacing mode in response to the temporary interval expiring.

28. The method of claim 16, further comprising delivering the ventricular pacing pulses via at least one electrode carried by a housing that encloses the pulse generator, the motion sensor, and the control circuit of the pacemaker.

29. A method performed by an intracardiac ventricular pacemaker having a motion sensor configured to produce a motion signal, the method comprising:

detecting a ventricular diastolic event from the motion signal;

detecting an atrial systolic event from the motion signal;

operating in a selected one of an atrial-tracking ventricular pacing mode and a non-atrial tracking ventricular pacing mode;

while operating in the selected one of the atrial-tracking ventricular pacing mode and the non-atrial tracking ventricular pacing mode, determining the at least one motion signal metric based on a time interval from the ventricular diastolic event to the atrial systolic event;

comparing the at least one motion signal metric to pacing mode switching criteria; and

responsive to the pacing mode switching criteria being satisfied, switching from the selected one of the non-atrial tracking pacing mode and the atrial tracking pacing mode to the other one of the non-atrial tracking pacing mode and the atrial tracking pacing mode for controlling ventricular pacing pulses delivered by the pacemaker.