Fluidic cartridge with valve mechanism
First Claim
Patent Images
1. A cartridge comprising:
- (a) a body comprising a malleable material; and
(b) a layer comprising a deformable material bonded to a surface of the body and sealing a fluidic channel that communicates with one or more valve bodies formed in a surface of the body;
wherein;
(i) the one or more valve bodies comprisea segment of the fluidic channel comprising a wall having a pair of ridges and a floor depressed into the surface,and(ii) the layer is bonded to the surface of the body and to the ridges such that the channel segment of the fluidic channel is sealed; and
wherein a valve body sealed with the layer forms a valve configured to regulate fluid flow in the fluidic channel and closable by forcing the layer against the floor of the segment of the channel.
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Abstract
Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.
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Citations
29 Claims
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1. A cartridge comprising:
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(a) a body comprising a malleable material; and (b) a layer comprising a deformable material bonded to a surface of the body and sealing a fluidic channel that communicates with one or more valve bodies formed in a surface of the body; wherein; (i) the one or more valve bodies comprise a segment of the fluidic channel comprising a wall having a pair of ridges and a floor depressed into the surface, and (ii) the layer is bonded to the surface of the body and to the ridges such that the channel segment of the fluidic channel is sealed; and wherein a valve body sealed with the layer forms a valve configured to regulate fluid flow in the fluidic channel and closable by forcing the layer against the floor of the segment of the channel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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Specification