Methods for measuring blood pressure
First Claim
1. A method of estimating a central systolic blood pressure (cSBP) of a human subject comprising:
- obtaining a peripheral blood pressure waveform of a pulse of a human subject and at least two peripheral blood pressure measurements over at least one cardiac cycle of the human subject from a blood pressure cuff placed about an arm of the human subject about a brachial artery when pressure in the blood pressure cuff is inflated to a sub-systolic pressure;
applying a transfer function to the obtained peripheral blood pressure waveform to provide an estimate of a central blood pressure waveform of the subject;
calibrating the obtained peripheral blood pressure waveform using the at least two peripheral blood pressure measurements, wherein the at least two peripheral blood pressure measurements comprise at least two of peripheral systolic blood pressure (pSBP), peripheral diastolic blood pressure (pDBP) and peripheral mean arterial pressure (pMAP); and
electronically estimating the cSBP of the human subject using the calibrated peripheral blood pressure waveform and the estimate of the central blood pressure waveform.
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Accused Products
Abstract
The application relates to an apparatus and a method for estimating a central systolic blood pressure (cSBP) of a subject, in which a peripheral blood pressure waveform of the subject'"'"'s pulse and at least two peripheral blood pressure measurements within the cardiac cycle of the subject are determined and the peripheral blood pressure waveform is manipulated with a transfer function to provide an estimate of the central blood pressure waveform of the subject'"'"'s pulse. The at least two peripheral blood pressure measurements within the cardiac cycle of the subject and the peripheral blood pressure waveform of the subject'"'"'s pulse are determined at substantially the same point on a peripheral artery of the subject. The estimate of the central blood pressure waveform of the subject'"'"'s pulse provides an estimate of the central systolic blood pressure of the subject.
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Citations
18 Claims
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1. A method of estimating a central systolic blood pressure (cSBP) of a human subject comprising:
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obtaining a peripheral blood pressure waveform of a pulse of a human subject and at least two peripheral blood pressure measurements over at least one cardiac cycle of the human subject from a blood pressure cuff placed about an arm of the human subject about a brachial artery when pressure in the blood pressure cuff is inflated to a sub-systolic pressure; applying a transfer function to the obtained peripheral blood pressure waveform to provide an estimate of a central blood pressure waveform of the subject; calibrating the obtained peripheral blood pressure waveform using the at least two peripheral blood pressure measurements, wherein the at least two peripheral blood pressure measurements comprise at least two of peripheral systolic blood pressure (pSBP), peripheral diastolic blood pressure (pDBP) and peripheral mean arterial pressure (pMAP); and electronically estimating the cSBP of the human subject using the calibrated peripheral blood pressure waveform and the estimate of the central blood pressure waveform. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 17, 18)
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10. A method of estimating a central systolic blood pressure (cSBP) comprising:
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obtaining a peripheral blood pressure waveform of a pulse of a human subject and at least two peripheral blood pressure measurements over at least one cardiac cycle of the human subject from a blood pressure cuff placed about a brachial artery of an arm of the human subject when pressure in the blood pressure cuff is inflated to a sub-systolic pressure; calibrating the obtained peripheral blood pressure waveform using the at least two peripheral blood pressure measurements, wherein the at least two peripheral blood pressure measurements comprise at least two of peripheral systolic blood pressure (pSBP), peripheral diastolic blood pressure (pDBP) and peripheral mean arterial pressure (pMAP); applying a transfer function to the obtained peripheral blood pressure waveform to provide an estimate of a central blood pressure waveform; and electronically estimating the cSBP of the human subject using the peripheral blood pressure waveform and with the calibration and the estimate of the central blood pressure waveform. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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Specification