Neurostimulation system with flexible patterning and waveforms

• US 10,213,608 B2
• Filed: 03/15/2017
• Issued: 02/26/2019
• Est. Priority Date: 07/03/2014
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Moffitt, Michael A.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US15/459,589
• Publication Number:
  US 20170182328A1
• Time in Patent Office: 713 Days
• Field of Search: None
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36135 using physiological parameters
• CPC Class Codes: A61N 1/36175 Pulse width or duty cycle
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A neurostimulation system configured for providing neurostimulation therapy to a patient. A user customizes a pulse pattern on a pulse-by-pulse basis. Electrical stimulation energy is delivered to at least one electrode in accordance with the customized pulse pattern.

Claims

1. A method for programming a neurostimulator to provide a neurostimulation therapy, comprising:

customizing a pulse pattern for the neurostimulation therapy on a pulse-by-pulse basis in response to user input; and

generating information for the neurostimulator, the neurostimulator configured to use the information to generate electrical stimulation energy in accordance with the customized pulse pattern for the neurostimulation therapy.

2. The method of claim 1, further comprising separately defining interpulse intervals between adjacent pairs of pulses in the pulse pattern in response to the user input.

3. The method of claim 1, further comprising separately defining widths of pulses in the pulse pattern in response to the user input.

4. The method of claim 1, wherein the neurostimulator includes a spinal cord stimulator, and customizing includes customizing the pulse pattern for a spinal cord stimulation therapy.

5. The method of claim 1, further comprising separately defining electrode combinations that deliver pulses in the pulse pattern in response to the user input.

6. The method of claim 1, further comprising adding or subtracting a pulse to or from the pulse pattern in response to the user input.

7. The method of claim 1, further comprising customizing the pulse pattern on the pulse-by-pulse basis by adjusting a multiplicative factor that is applied to a baseline stimulation parameter of the pulse pattern in response to the user input.

8. The method of claim 1, further comprising generating a program for an application specific integrated circuit to generate the customized pulse pattern.

9. The method of claim 1, further comprising displaying the pulse pattern, and customizing the pulse pattern based on user input corresponding to a drag, using a pointing element, of a portion of the displayed pulse pattern.

10. The method of claim 1, further comprising limiting the customizing of the pulse pattern in accordance with a set of heuristic safety/regulatory rules.

11. The method of claim 1, further comprising:

in response to the user input, selecting one or more of a plurality of different customized pulse patterns stored in a memory; and

generating information for the neurostimulator to deliver the electrical stimulation energy in accordance with the selected one or more of the plurality of different customized pulse patterns.

12. The method of claim 1, further comprising customizing another pulse pattern on a pulse-by-pulse basis in response to the user input, and generating information for the neurostimulator to deliver the electrical stimulation energy in accordance with the customized pulse pattern and to concurrently deliver electrical stimulation energy in accordance with the other customized pulse pattern in a respective timing channel.

13. The method of claim 12, further comprising defining a phase offset between the customized pulse pattern and the other customized pulse pattern within the respective timing channels in response to the user input.

14. The method of claim 1, further comprising globally modifying a stimulation parameter for a plurality of pulses of a tonic pulse pattern in response to the user input, and generating instructions for the neurostimulator to deliver the electrical stimulation energy to the patient in accordance with the tonic pulse pattern.

15. The method of claim 1, further comprising exporting the customized pulse pattern to a central database accessible to a plurality of users.

16. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to program a neurostimulator to provide a neurostimulation therapy, including:

customize a pulse pattern for the neurostimulation therapy on a pulse-by-pulse basis in response to user input; and

generate information for the neurostimulator, the neurostimulator configured to use the information to generate electrical stimulation energy in accordance with the customized pulse pattern for the neurostimulation therapy.

17. The non-transitory machine-readable medium of claim 16, further comprising instructions, which when executed by the machine, cause the machine to:

define the interpulse intervals between adjacent pairs of pulses in the pulse pattern in response to the user input.

18. The non-transitory machine-readable medium of claim 16, further comprising instructions, which when executed by the machine, cause the machine to add or subtract a pulse to or from the pulse pattern in response to the user input.

19. The non-transitory machine-readable medium of claim 16, further comprising instructions, which when executed by the machine, cause the machine to:

select one or more of a plurality of different customized pulse patterns stored in a memory in response to the user input;

generate information for the neurostimulator to generate electrical stimulation energy in accordance with the selected one or more of the plurality of different customized pulse patterns.

20. A system for programming a neurostimulator to provide a neurostimulation therapy, the system comprising at least one device including processing circuitry, the system being configured to use the at least one device including processing circuitry to:

customize a pulse pattern for the neurostimulation therapy on a pulse-by-pulse basis in response to user input; and

generate information for the neurostimulator, the neurostimulator configured to use the information to generate electrical stimulation energy in accordance with the customized pulse pattern for the neurostimulation therapy.