Locating and analyzing perforator flaps for plastic and reconstructive surgery
First Claim
Patent Images
1. A method for evaluating tissue perfusion in a tissue of a subject, the method comprising:
- detecting, through a skin surface, a fluorescence response from the tissue arising from a bolus of ICG having been administered into the bloodstream of the subject;
acquiring a temporal sequence of images of the fluorescence response over a period of time;
independently processing each pixel in the temporal sequence of images of the tissue to (i) compute a temporally-based value for each pixel, wherein each temporally-based value is based on a plurality of images of the temporal sequence of images, and (ii) generate a spatial map of the computed temporally-based values; and
displaying the spatial map of the computed temporally-based values,wherein each temporally-based value is a peak value of the fluorescence response for the respective pixel.
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Abstract
A method and an apparatus for preoperative identification of a perforator vessel for plastic and/or reconstructive surgery using ICG fluorescence angiography imaging are disclosed. Time-resolved image processing is used to highlight perforator locations and to enable visual discrimination among candidate perforators by various computed metrics. Based on these metrics, the surgeon is able to interactively locate and select perforator vessels suitable for plastic and reconstructive surgery.
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Citations
20 Claims
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1. A method for evaluating tissue perfusion in a tissue of a subject, the method comprising:
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detecting, through a skin surface, a fluorescence response from the tissue arising from a bolus of ICG having been administered into the bloodstream of the subject; acquiring a temporal sequence of images of the fluorescence response over a period of time; independently processing each pixel in the temporal sequence of images of the tissue to (i) compute a temporally-based value for each pixel, wherein each temporally-based value is based on a plurality of images of the temporal sequence of images, and (ii) generate a spatial map of the computed temporally-based values; and displaying the spatial map of the computed temporally-based values, wherein each temporally-based value is a peak value of the fluorescence response for the respective pixel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. An apparatus for evaluating perforator vessels in candidate perforator flaps, comprising:
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means for detecting a fluorescence response from blood-carried ICG in the perforator vessels in the candidate perforator flaps; means for acquiring a temporal sequence of images of the fluorescence response over a predetermined time; means for processing the sequence of images to yield a time-integrated intensity or time-derivative of the intensity for pixel values in the images corresponding to the blood-carried ICG in the perforator vessels in the candidate perforator flaps, said means for processing including an algorithm that inversely weights the pixel values in relation to elapsed time from application of an ICG bolus into the bloodstream until fluorescence; and means for displaying the time-integrated intensity or time-derivative of the intensity as a color or black-and-white image.
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19. An apparatus for evaluating tissue perfusion in a tissue of a subject, comprising:
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a camera configured to detect, through a skin surface, a fluorescence response from the tissue arising from a bolus of ICG having been administered into the bloodstream of the subject; a processor configured to acquire a temporal sequence of images of the fluorescence response over a period of time, and independently process each pixel in the temporal sequence of images of the tissue to (i) compute a temporally-based value for each pixel, wherein each temporally-based value is based on a plurality of images of the temporal sequence of images, and (ii) generate a spatial map of the computed temporally-based values; and a display configured to display the spatial map of the computed temporally-based values, wherein each temporally-based value is a peak value of the fluorescence response for the respective pixel. - View Dependent Claims (20)
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Specification